SCHEMBL23503283

SCHEMBL23503283

N#Cc1cccc(C#N)c1-c1cccc(-n2c3ccccc3c3ccc4c(c5ccccc5n4-c4ccc(-c5ccccc5)cc4)c32)c1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
HPGD P15428 1/20 0.34
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HDAC4 P56524 1/20 0.32
KMT2A Q03164 1/20 0.32
EDNRB P24530 1/20 0.31
EDNRA P25101 1/20 0.31
NR3C1 P04150 1/20 0.31
MAOA P21397 1/20 0.31
IL1R1 P14778 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23503009 1.00 KDM4E (0.38) KDM4EATML3MBTL1ALDH1A1LMNA
SCHEMBL23503172 0.97 L3MBTL1 (0.41) KDM4EATML3MBTL1ALDH1A1LMNA
SCHEMBL23503028 0.97 L3MBTL1 (0.41) KDM4EATML3MBTL1ALDH1A1LMNA
SCHEMBL23503233 0.96 ATM (0.37) KDM4EATML3MBTL1ALDH1A1LMNA
SCHEMBL23503176 0.96 ATM (0.37) KDM4EATML3MBTL1ALDH1A1LMNA
SCHEMBL23503284 0.94 KDM4E (0.35) KDM4EATML3MBTL1ALDH1A1LMNA
SCHEMBL23503010 0.94 KDM4E (0.35) KDM4EATML3MBTL1ALDH1A1LMNA
SCHEMBL23503084 0.92 KDM4E (0.40) KDM4EATML3MBTL1ALDH1A1LMNA
SCHEMBL23503061 0.91 KDM4E (0.41) KDM4EATML3MBTL1ALDH1A1LMNA
SCHEMBL23503043 0.90 KDM4E (0.31) KDM4EATML3MBTL1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11038117-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-06-15 US disclosed