SCHEMBL2350424

SCHEMBL2350424

CC(=O)c1cccc(Oc2ccccc2)c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AKR1C3 P42330 1/20 0.72
▸ MEN1 O00255 2/20 0.65
▸ KMT2A Q03164 2/20 0.65
▸ HDAC8 Q9BY41 1/20 0.64
▸ MAOB P27338 1/20 0.63
▸ ERCC5 P28715 1/20 0.58
▸ FEN1 P39748 1/20 0.58
▸ MAPT P10636 3/20 0.58
▸ CRHBP P24387 1/20 0.58
▸ HTT P42858 1/20 0.58
▸ CRHR2 Q13324 1/20 0.58
▸ TLR4 O00206 1/20 0.58
▸ TLR2 O60603 1/20 0.58
▸ CYP1A2 P05177 1/20 0.57
▸ TNKS O95271 1/20 0.56
▸ PARP15 Q460N3 1/20 0.56
▸ PARP14 Q460N5 1/20 0.56
▸ PARP10 Q53GL7 1/20 0.56
▸ TNKS2 Q9H2K2 1/20 0.56
▸ PARP2 Q9UGN5 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25620248 0.94 MEN1 (0.71) AKR1C3MEN1KMT2AHDAC8MAOB
SCHEMBL564525 0.91 RAB9A (0.70) AKR1C3MEN1KMT2AHDAC8MAOB
SCHEMBL10970400 0.87 MEN1 (0.59) AKR1C3MEN1KMT2AMAOBMAPT
SCHEMBL25910311 0.87 MAOB (0.63) AKR1C3MEN1KMT2AHDAC8MAOB
SCHEMBL18758803 0.87 MEN1 (0.59) AKR1C3MEN1KMT2AMAPTTNKS
SCHEMBL8736479 0.87 MAOB (0.63) AKR1C3MEN1KMT2AHDAC8MAOB
SCHEMBL23052979 0.86 AKR1C3 (0.58) AKR1C3MEN1KMT2AHDAC8MAOB
SCHEMBL17895544 0.86 MAOB (0.64) AKR1C3MEN1KMT2AHDAC8MAOB
SCHEMBL2264913 0.86 MEN1 (0.58) AKR1C3MEN1KMT2AHDAC8MAOB
SCHEMBL2563940 0.86 AKR1C3 (0.74) AKR1C3MEN1KMT2AHDAC8MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119591490-A Preparation method of fenoprofen and preparation method of fenoprofen calcium 康普药业股份有限公司 2025-03-11 — — CN claimed
CN-119504402-A Fenoprof Synthesis method of Fenne 南京工业大学 2025-02-25 — — CN claimed
CN-116354850-B Preparation method of fenpropathrin 大连凯飞化学股份有限公司 2024-02-13 — — CN claimed
CN-116354850-A Preparation method of fenpropathrin 大连凯飞化学股份有限公司 2023-06-30 — — CN claimed
CN-116041212-A Preparation and application of difluoro olefin ether and oxime ether derivatives 安徽农业大学 2023-05-02 — — CN claimed
CN-114014807-B Preparation method of key intermediate of roxasistat 天津力生制药股份有限公司 2023-01-17 — — CN claimed
CN-114014807-A Preparation method of key intermediate of roxasistat 天津力生制药股份有限公司 2022-02-08 — — CN claimed
CN-113072495-A Preparation method of intermediate of roxasistat 上海法默生物科技有限公司 2021-07-06 — — CN claimed
CN-108690018-A A kind of Mi Zuobing [1,2-a]The preparation method of pyridine derivate 郑州大学 2018-10-23 — — CN claimed
CN-105980491-A Coated nanoparticle catalytically active composite inks 伊斯曼柯达公司 2016-09-28 — — CN claimed
CN-105541607-A Method for synthesizing 4-phenoxybenzoyl chloride, important intermediate of ibrutinib JIANGSU HEZHIRUN BIOTECHNOLOGY CO LTD 2016-05-04 — — CN claimed
CN-104508794-A Ink formulations for flexographic printing of high-resolution conducting patterns UNIPIXEL DISPLAYS INC 2015-04-08 — — CN claimed
CN-1003043-B Synthesis method of m-phenoxy acetophenone 山东新华制药厂 1989-01-11 — — CN claimed
CN-86105054-A The synthetic method of 1-(3-Phenoxyphenyl)ethanone — 1987-02-11 — — CN claimed
JP-58067640-A — — None — — JP disclosed
US-12637436-B2 Metabotropic glutamate receptor negative allosteric modulators (NAMs) and uses thereof Sanford Burnham Prebys Medical Discovery Institute (US) 2026-05-26 — — US disclosed
CN-120987752-A Preparation method of fenoprofen calcium 康普药业股份有限公司 2025-11-21 — — CN disclosed
US-3991212-A PHENYLACETYLENE COMPOUNDS ELI LILLY AND COMPANY (US) 1976-11-09 — — US disclosed
US-3972934-A ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC ELI LILLY AND COMPANY (US) 1976-08-03 — — US disclosed
US-3939278-A Phenoxyphenyl-acetylenes and thio analogues thereof as antithrombotic agents ELI LILLY AND COMPANY (US) 1976-02-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637436-B2 Metabotropic glutamate receptor negative allosteric modulators (NAMs) and uses thereof GRM3, GRM2, GRM1 AKR1C3 3731/4885MEN1 2193/4885KMT2A 1325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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