Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TLR4 | O00206 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 1/20 | 0.47 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12604608 | 0.89 | AKR1C3 (0.51) | AKR1C3MAPTHPGDRAB9AHDAC8 | |
| SCHEMBL2350424 | 0.86 | AKR1C3 (0.72) | AKR1C3MAPTHPGDRAB9AHDAC8 | |
| SCHEMBL167640 | 0.83 | RAB9A (0.83) | MAPTHPGDRAB9AMAOBPARP10 | |
| SCHEMBL5747830 | 0.83 | AKR1C3 (0.74) | AKR1C3HDAC8PARP10MEN1KMT2A | |
| SCHEMBL3439666 | 0.82 | MAPT (0.61) | MAPTHPGDRAB9AMAOBMEN1 | |
| SCHEMBL12742894 | 0.81 | GCK (0.61) | — | |
| SCHEMBL22210569 | 0.81 | TSHR (0.59) | AKR1C3MAPTHPGDRAB9AHDAC8 | |
| SCHEMBL12220509 | 0.81 | MAPT (0.59) | MAPTHPGDRAB9APARP10MEN1 | |
| Diphenylether SCHEMBL28412058 | 0.80 | LTA4H (0.67) | AKR1C3MAPTHPGDRAB9APARP10 | |
| Diphenylether SCHEMBL29175285 | 0.80 | LTA4H (0.67) | AKR1C3MAPTHPGDRAB9APARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220393118-A1 | TETRADENTATE LIGANDS, GOLD(III) COMPLEXES, PREPARATION METHOD AND USE THEREOF | CHE, CHI MING (CN) | 2022-12-08 | — | — | US | disclosed |
| WO-2021036978-A1 | TETRADENTATE LIGANDS, GOLD(III) COMPLEXES, PREPARATION METHOD AND USE THEREOF | CHE CHI MING (CN) | 2021-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220393118-A1 | TETRADENTATE LIGANDS, GOLD(III) COMPLEXES, PREPARATION METHOD AND USE THEREOF | PDCD2L, TTL, TTLL12 | AKR1C3 3054/4885MAPT 20/4885HPGD 4495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.