Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16214710 | 0.75 | KMT2A (0.37) | RAB9AALDH1A1KDM4ENPSR1L3MBTL1 | |
| SCHEMBL27254458 | 0.73 | MAOA (0.40) | RAB9ASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL15668887 | 0.72 | KMT2A (0.42) | RAB9ASMN1; SMN2ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL15669107 | 0.72 | ALDH1A1 (0.35) | RAB9ASMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL15668691 | 0.70 | ALDH1A1 (0.61) | RAB9ASMN1; SMN2ALDH1A1KDM4EPOLB | |
| Acetic Acid SCHEMBL28089005 | 0.68 | ALDH1A1 (0.40) | RAB9ASMN1; SMN2ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL28005595 | 0.67 | KDM4E (0.42) | ALDH1A1KDM4EKMT2AHPGDTSHR | |
| SCHEMBL11922540 | 0.67 | ALDH1A1 (0.45) | RAB9ASMN1; SMN2ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL2608954 | 0.66 | KMT2A (0.58) | RAB9ASMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL24057956 | 0.66 | MAOA (0.37) | RAB9ASMN1; SMN2ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3835322-A2 | ANTI-B7-H3 ANTIBODIES AND ANTIBODY DRUG CONJUGATES | AbbVie Inc. (US) | 2021-06-16 | — | — | EP | disclosed |