Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2355362 | 0.84 | — | — | |
| SCHEMBL2356693 | 0.84 | ADRA1D (0.30) | — | |
| SCHEMBL2349987 | 0.79 | GRM2 (0.31) | — | |
| SCHEMBL2353890 | 0.75 | SLC10A2 (0.37) | KDM1AKDM1B | |
| SCHEMBL2355061 | 0.73 | KDM1A (0.38) | KDM1AKDM1B | |
| SCHEMBL2355107 | 0.73 | ADRA1D (0.30) | — | |
| SCHEMBL2355899 | 0.73 | KDM1A (0.35) | KDM1AKDM1B | |
| SCHEMBL2353872 | 0.71 | CXCR2 (0.32) | — | |
| SCHEMBL2357728 | 0.70 | MEN1 (0.34) | — | |
| SCHEMBL2357699 | 0.69 | CA1 (0.35) | CTSLKDM1AKDM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011083264-A1 | THIOCHROMAN DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2011-07-14 | — | — | WO | claimed |
| WO-2011083264-A1 | THIOCHROMAN DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2011-07-14 | — | — | WO | disclosed |