SCHEMBL2351222

SCHEMBL2351222

c1cc2[nH]cnn2c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10445950 0.63
SCHEMBL63061 0.58
SCHEMBL25472754 0.57 MAP4K4 (0.39)
Hydrochloric Acid SCHEMBL8134374 0.56 ALOX15 (0.36)
SCHEMBL25045803 0.56 EPHB3 (0.36)
SCHEMBL24458554 0.56 NR1H2 (0.33)
SCHEMBL5566002 0.54
SCHEMBL2351390 0.54
SCHEMBL24548207 0.52 MAP4K4 (0.44)
SCHEMBL5487950 0.41

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3704097-B1 BICYCLIC SULFONES AND SULFOXIDES AND METHODS OF USE THEREOF HOFFMANN LA ROCHE (CH) 2023-10-25 EP claimed
US-7288123-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2007-10-30 US claimed
WO-2007071686-A1 COMPOSITION FOR DYEING KERATIN FIBRES WITH A TETRAAZAPENTAMETHINE CATIONIC DIRECT DYE, AN OXIDATION BASE AND A PARTICULAR COUPLER L'ORÉAL (FR) 2007-06-28 WO claimed
EP-1781237-A1 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF The Procter and Gamble Company (US) 2007-05-09 EP claimed
EP-0857726-B1 1H-pyrrolo-¬1,2-b|¬1,2,4|triazole compound and its synthetic intermediate, and method of preparing a 1H-1,2,4-trazole-5-yl-acetic acid ester compound FUJI PHOTO FILM CO LTD (JP) 2006-06-14 EP claimed
WO-2006026432-A1 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2006-03-09 WO claimed
US-20060042024-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof NOXELL CORPORATION 2006-03-02 US claimed
US-20040231067-A1 Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses L'OREAL (FR) 2004-11-25 US claimed
EP-0714892-B1 1H-pyrrolo [1, 2-b][1, 2, 4] Triazole derivatives and their preparation via 1H-1,2,4-triazole derivatives FUJI PHOTO FILM CO LTD (JP) 2004-01-07 EP claimed
US-20030187188-A1 Synthesis of peptoid substituted azole compounds EASTMAN KODAK COMPANY 2003-10-02 US claimed
US-6171773-B1 CONTAINS PYRROLO(1,2-B)-1,2,4-TRIAZOLE CYAN COUPLER AGFA N.V (BE) 2001-01-09 US claimed
EP-0518238-B1 Pyrrolotriazole derivative FUJI PHOTO FILM CO LTD (JP) 1999-04-07 EP claimed
EP-0720981-B1 Cyclohexyloxycarbonylacetohydrazides and method for producing 1H-1,2,4-triazoles using the hydrazides FUJI PHOTO FILM CO LTD (JP) 1998-10-14 EP claimed
EP-0857726-A1 1H-pyrrolo-[1,2-b][1,2,4]triazole compound and its synthetic intermediate, and method of preparing a 1H-1,2,4-trazole-5-yl-acetic acid ester compound FUJI PHOTO FILM CO., LTD. (JP) 1998-08-12 EP claimed
EP-0491197-B1 Cyan image forming method and silver halide color photographic material containing cyan coupler FUJI PHOTO FILM CO LTD (JP) 1997-03-12 EP claimed
EP-0720981-A1 Cyclohexyloxycarbonylacetohydrazides and method for producing 1H-1,2,4-triazoles using the hydrazides FUJI PHOTO FILM CO., LTD. (JP) 1996-07-10 EP claimed
EP-0714892-A1 1H-pyrrolo [1, 2-b][1, 2, 4] Triazole derivatives and their preparation via 1H-1,2,4-triazole derivatives FUJI PHOTO FILM CO., LTD. (JP) 1996-06-05 EP claimed
US-5256526-A Form high color density colorfast images FUJI PHOTO FILM CO., LTD. (JP) 1993-10-26 US claimed
EP-0518238-A1 Pyrrolotriazole derivative FUJI PHOTO FILM CO., LTD. (JP) 1992-12-16 EP claimed
EP-0491197-A1 Cyan image forming method and silver halide color photographic material containing cyan coupler FUJI PHOTO FILM CO., LTD. (JP) 1992-06-24 EP claimed