SCHEMBL63061

SCHEMBL63061

c1cnn2cccc2c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8134374 0.97 ALOX15 (0.36)
Hydrochloric Acid SCHEMBL28275439 0.97 ALOX15 (0.36)
SCHEMBL27747566 0.87 ALOX15 (0.62)
SCHEMBL31391 0.81
Hydrochloric Acid SCHEMBL30373465 0.79 ALOX15 (0.40)
Hydrochloric Acid SCHEMBL30373752 0.79 ALOX15 (0.40)
SCHEMBL9517406 0.77 ALOX15 (0.62)
SCHEMBL15011631 0.75 DYRK1A (0.38)
Pyridine SCHEMBL27834852 0.75 ALDH1A1 (0.41)
Pyrimidine SCHEMBL15020699 0.72 ALOX15 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2686 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12595265-B2 Inhibitors of activin receptor-like kinase BLUEPRINT MEDICINES CORPORATION (US) 2026-04-07 US claimed
EP-4463457-B1 PYRROLO[1,2-B]-2-PYRIDAZINONE COMPOUNDS AS 5-HT4 RECEPTOR AGONISTS SUVEN LIFE SCIENCES LTD (IN) 2026-02-04 EP claimed
EP-4658655-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES Beone Medicines I GmbH (CH) 2025-12-10 EP claimed
US-20250353858-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES BEONE MEDICINES I GMBH (CH) 2025-11-20 US claimed
WO-2024160278-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES BEIGENE, LTD. (KY) 2024-08-08 WO claimed
WO-2024106781-A1 LIPID COMPOUND AND COMPOSITION FOR DELIVERY OF ACTIVE SUBSTANCE 한국생명공학연구원 2024-05-23 WO claimed
US-20240158398-A1 INHIBITORS OF ACTIVIN RECEPTOR-LIKE KINASE BLUEPRINT MEDICINES CORPORATION 2024-05-16 US claimed
EP-3442977-B1 INHIBITORS OF ACTIVIN RECEPTOR-LIKE KINASE BLUEPRINT MEDICINES CORP (US) 2023-06-28 EP claimed
US-11634422-B2 Inhibitors of activin receptor-like kinase BLUEPRINT MEDICINES CORPORATION (US) 2023-04-25 US claimed
US-20220315585-A1 INHIBITORS OF ACTIVIN RECEPTOR-LIKE KINASE BLUEPRINT MEDICINES CORPORATION 2022-10-06 US claimed
US-20170107178-A1 INDOLE DERIVATIVES FOR USE IN MEDICINE IOMET PHARMA LTD. (GB) 2017-04-20 US claimed
EP-3125883-A1 INDOLE DERIVATIVES FOR USE IN MEDICINE Iomet Pharma Ltd. (GB) 2017-02-08 EP claimed
WO-2015150097-A1 INDOLE DERIVATIVES FOR USE IN MEDICINE IOMET PHARMA LTD (GB) 2015-10-08 WO claimed
US-20130303563-A1 TREATMENT OF PERITONEAL INJURY USING JAK INHIBITORS LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER 2013-11-14 US claimed
EP-1651647-A1 NICOTINAMIDE DERIVATIVES USEFUL AS PDEA4 INHIBITORS Pfizer Limited (GB) 2006-05-03 EP claimed
WO-2005010001-A1 NICOTINAMIDE DERIVATIVES USEFUL AS PDEA4 INHIBITORS PFIZER LIMITED (GB) 2005-02-03 WO claimed
US-6472389-B1 Pyrrolo[1,2-b] pyridazine derivatives having sPLA2 inhibitory effect SHIONOGI & CO., LTD. (JP) 2002-10-29 US claimed
CN-1302300-A Pyrrolo [1, 2-b]Pyridazine sPLA2Inhibitors SHIONOGI & CO (JP) 2001-07-04 CN claimed
EP-1085021-A1 PYRROLO 1,2-b]PYRIDAZINE DERIVATIVES HAVING sPLA 2? INHIBITORY EFFECT SHIONOGI & CO., LTD. (JP) 2001-03-21 EP claimed
US-5391468-A With emulsion layer containing blend of spectrally sensitized tabular iodohalide grains and second, slower, fine grain population of higher solubility silver salt content having second dye adsorbed to surface EASTMAN KODAK COMPANY (US) 1995-02-21 US claimed