Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.46 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15927526 | 0.92 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2LMNAEHMT2EHMT1 | |
| SCHEMBL27383058 | 0.87 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2LMNAEHMT2EHMT1 | |
| SCHEMBL17748162 | 0.87 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2LMNAEHMT2EHMT1 | |
| SCHEMBL17752518 | 0.87 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2LMNAEHMT2EHMT1 | |
| SCHEMBL579460 | 0.87 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2LMNAEHMT2EHMT1 | |
| SCHEMBL18811278 | 0.86 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2LMNAKMT2ARAB9A | |
| SCHEMBL18805587 | 0.86 | LMNA (0.62) | ALDH1A1SMN1; SMN2LMNAEHMT2EHMT1 | |
| SCHEMBL15907906 | 0.86 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2LMNAEHMT2EHMT1 | |
| SCHEMBL17072457 | 0.84 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2LMNAKMT2AMAPT | |
| SCHEMBL10064444 | 0.83 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2LMNAEHMT2EHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113039191-B | Nucleotide analogues | 奇异基因组学系统公司 | 2024-07-16 | — | — | CN | disclosed |
| US-20210179720-A1 | NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF | AVIDITY BIOSCIENCES, INC. | 2021-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210179720-A1 | NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND USES THEREOF | POLM, POLN, POLI | ALDH1A1 4316/4885SMN1; SMN2 465/4885LMNA 280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.