Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25146548 | 0.86 | FFAR1 (0.45) | CYP4F2CYP4A11MAPTTSHRLMNA | |
| SCHEMBL13823861 | 0.83 | MAPT (0.51) | MAPTTSHRTDP1MGLLPDCD1 | |
| SCHEMBL23512353 | 0.81 | HSD17B10 (0.54) | CYP4F2CYP4A11MAPTTSHRLMNA | |
| SCHEMBL4420191 | 0.81 | CA12 (0.50) | CYP4F2CYP4A11MAPTTSHRLMNA | |
| SCHEMBL19024861 | 0.81 | L3MBTL1 (0.59) | CYP4F2CYP4A11MAPTTSHRLMNA | |
| SCHEMBL23287934 | 0.80 | IDO1 (0.47) | CYP4F2CYP4A11MAPTTSHRLMNA | |
| SCHEMBL9350223 | 0.80 | CYP4F2 (0.46) | CYP4F2CYP4A11TSHRLMNAALDH1A1 | |
| SCHEMBL22652835 | 0.80 | CYP4F2 (0.46) | CYP4F2CYP4A11MAPTTSHRLMNA | |
| SCHEMBL10020494 | 0.80 | FKBP1A (0.52) | CYP4F2CYP4A11MAPTTSHRLMNA | |
| SCHEMBL23512483 | 0.80 | CYP4F2 (0.70) | CYP4F2CYP4A11TDP1FFAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021119249-A1 | CYCLOPHILIN D INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2021-06-17 | — | — | WO | disclosed |