Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25146694 | 0.91 | CYP4F2 (0.51) | CYP4F2CYP4A11TDP1HRH3CYP4Z1 | |
| SCHEMBL23512483 | 0.85 | CYP4F2 (0.70) | CYP4F2CYP4A11TDP1HRH3CYP4Z1 | |
| SCHEMBL25146512 | 0.84 | CYP4F2 (0.44) | CYP4F2CYP4A11TDP1HRH3FFAR1 | |
| SCHEMBL23512353 | 0.80 | HSD17B10 (0.54) | CYP4F2CYP4A11TDP1HRH3FFAR1 | |
| SCHEMBL879130 | 0.80 | CYP4F2 (0.77) | CYP4F2CYP4A11TDP1HRH3CYP4Z1 | |
| SCHEMBL26036263 | 0.78 | KMT2A (0.55) | CYP4F2CYP4A11FFAR1HSD17B10LMNA | |
| SCHEMBL26036272 | 0.78 | KMT2A (0.55) | CYP4F2CYP4A11FFAR1HSD17B10LMNA | |
| SCHEMBL23512481 | 0.76 | CYP4F2 (0.47) | CYP4F2CYP4A11TDP1HRH3FFAR1 | |
| SCHEMBL11894639 | 0.76 | CYP4F2 (0.70) | CYP4F2CYP4A11TDP1HRH3CYP4Z1 | |
| SCHEMBL23512465 | 0.74 | FFAR1 (0.71) | HRH3FFAR1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021119249-A1 | CYCLOPHILIN D INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2021-06-17 | — | — | WO | disclosed |