Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6264512 | 0.98 | DNM1 (0.46) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL6297062 | 0.98 | DNM1 (0.46) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Octane SCHEMBL9464723 | 0.83 | DNM1 (0.65) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Ammonia Solution, Strong SCHEMBL6056099 | 0.83 | OPRM1 (0.48) | DNM1ALDH1A1TSHRSPHK1OPRM1 | |
| Ammonia Solution, Strong SCHEMBL1971792 | 0.83 | OPRM1 (0.48) | DNM1ALDH1A1TSHRSPHK1OPRM1 | |
| Ammonia Solution, Strong SCHEMBL7004796 | 0.83 | OPRM1 (0.48) | DNM1ALDH1A1TSHRSPHK1OPRM1 | |
| Ammonia Solution, Strong SCHEMBL28091200 | 0.83 | OPRM1 (0.48) | DNM1ALDH1A1TSHRSPHK1OPRM1 | |
| Ammonia Solution, Strong SCHEMBL5704521 | 0.83 | OPRM1 (0.48) | DNM1ALDH1A1TSHRSPHK1OPRM1 | |
| Ammonia Solution, Strong SCHEMBL11232861 | 0.83 | OPRM1 (0.48) | DNM1ALDH1A1TSHRSPHK1OPRM1 | |
| Ammonia Solution, Strong SCHEMBL5072902 | 0.83 | OPRM1 (0.48) | DNM1ALDH1A1TSHRSPHK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1196371-B1 | QUATERNARY BIS-AMMONIUM SALT PRECURSORS AND THEIR USES AS PRODRUGS HAVING AN ANTIPARASITIC ACTIVITY | CENTRE NAT RECH SCIENT (FR) | 2005-11-02 | — | — | EP | claimed |
| EP-2252286-B1 | COMBINATION OF A BIS-THIAZOLIUM SALT OR A PRECURSOR THEREOF AND ARTEMISININ OR A DERIVATIVE THEREOF FOR TREATING ACUTE MALARIA | SANOFI SA (FR) | 2011-08-24 | — | — | EP | disclosed |