Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15461461 | 0.85 | ALDH1A1 (0.37) | MMEFFAR3CYP1A2 | |
| SCHEMBL12869547 | 0.80 | ALDH1A1 (0.37) | MMEFFAR3CYP1A2 | |
| SCHEMBL12869545 | 0.78 | ALDH1A1 (0.36) | MMEFFAR3CYP1A2 | |
| SCHEMBL12258930 | 0.78 | ALDH1A1 (0.38) | MMEFFAR3CYP1A2 | |
| SCHEMBL21844010 | 0.78 | ALDH1A1 (0.40) | MME | |
| SCHEMBL21844029 | 0.76 | MME (0.34) | MME | |
| SCHEMBL11516694 | 0.75 | CYP2C19 (0.33) | MMEFFAR3CYP1A2 | |
| SCHEMBL20988109 | 0.73 | CA12 (0.31) | FFAR3 | |
| SCHEMBL805255 | 0.72 | — | — | |
| SCHEMBL3259891 | 0.71 | LMNA (0.51) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210179580-A1 | PYRIMIDINE DERIVATIVES AS INHIBITORS OF PD1/PD-L1 ACTIVATION | Jubilant Prodel LLC | 2021-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210179580-A1 | PYRIMIDINE DERIVATIVES AS INHIBITORS OF PD1/PD-L1 ACTIVATION | PDCD1, CD274, PDCD1LG2 | MME 4459/4885FFAR3 3706/4885CYP1A2 241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.