SCHEMBL2351402

SCHEMBL2351402

O=C(O)Oc1sc(C(F)(F)C(F)(F)F)nc1C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.32
NPC1 O15118 1/20 0.31
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2428792 0.78 MAPT (0.47) MAPTNPC1PKM
SCHEMBL1417177 0.77 ALDH1A1 (0.39) MAPTNPC1PKM
SCHEMBL9676927 0.77 MEN1 (0.37) MAPTNPC1PKM
SCHEMBL2362831 0.70 ALDH1A1 (0.49) MAPT
SCHEMBL6209005 0.66 MAPT (0.43) MAPT
SCHEMBL27397703 0.66 MEN1 (0.36) MAPT
SCHEMBL27267502 0.64 MAPT (0.40) MAPTNPC1
SCHEMBL7552055 0.63 MEN1 (0.37) MAPT
SCHEMBL2352670 0.62 KDM4E (0.31)
SCHEMBL12647580 0.62 MAPT (0.39) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2352723-B1 PESTICIDAL N-ARYL- OR N-HETEROARYL PYRAZOLE CARBOXAMIDE COMPOUNDS BAYER IP GMBH (DE) 2016-11-23 EP disclosed
EP-2352723-A2 HALOGEN-SUBSTITUTED COMPOUNDS USED AS PESTICIDES Bayer CropScience AG (DE) 2011-08-10 EP disclosed
WO-2010051926-A2 NEW HALOGEN-SUBSTITUTED BONDS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2010-05-14 WO disclosed