Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | COMT | P21964 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6209005 | 0.86 | MAPT (0.43) | MAPTPOLBALDH1A1GAACOMT | |
| SCHEMBL27267502 | 0.83 | MAPT (0.40) | MAPTPOLBALDH1A1GAACOMT | |
| SCHEMBL12647580 | 0.82 | MAPT (0.39) | MAPTPOLBALDH1A1GAACOMT | |
| SCHEMBL1417177 | 0.81 | ALDH1A1 (0.39) | MAPTPOLBALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9676927 | 0.81 | MEN1 (0.37) | MAPTPOLBALDH1A1NPC1PKM | |
| SCHEMBL2351402 | 0.78 | MAPT (0.32) | MAPTNPC1PKM | |
| SCHEMBL486254 | 0.75 | RAB9A (0.39) | MAPTALDH1A1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL975710 | 0.74 | MAPT (0.60) | MAPTPOLBALDH1A1GAACOMT | |
| SCHEMBL5237956 | 0.73 | RAB9A (0.33) | MAPTALDH1A1SMN1; SMN2NPC1KMT2A | |
| SCHEMBL31567863 | 0.72 | MAPT (0.34) | MAPTPOLBALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001892-B1 | IMIDAZOLOTHIAZOLE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISEASES | AMBIT BIOSCIENCES CORP (US) | 2013-04-24 | — | — | EP | claimed |
| EP-1966161-B1 | CARBOXAMIDES FOR CONTROLLING UNDESIRED MICRO-ORGANISMS IN PLANT PROTECTION | BAYER CROPSCIENCE AG (DE) | 2011-09-28 | — | — | EP | disclosed |
| EP-1888545-B1 | THIAZOLE CARBOXYLIC ACID ANILIDES | BASF SE (DE) | 2010-08-25 | — | — | EP | disclosed |
| EP-1966161-A1 | CARBOXAMIDES FOR CONTROLLING UNDESIRED MICRO-ORGANISMS IN PLANT PROTECTION | Bayer CropScience AG (DE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2008053044-A2 | HETARYL CARBON ACID-N-(BIPHEN-2-YL)AMIDE COMPOUNDS | BASF SE (DE) | 2008-05-08 | — | — | WO | disclosed |
| EP-1888545-A1 | THIAZOLE CARBOXYLIC ACID ANILIDES | BASF AKTIENGESELLSCHAFT (DE) | 2008-02-20 | — | — | EP | disclosed |
| WO-2007068375-A1 | CARBOXAMIDES FOR CONTROLLING UNDESIRED MICRO-ORGANISMS IN PLANT PROTECTION | BAYER CROPSCIENCE AG (DE) | 2007-06-21 | — | — | WO | disclosed |
| WO-2006122933-A1 | THIAZOLE CARBOXYLIC ACID ANILIDES | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-23 | — | — | WO | disclosed |