SCHEMBL23514531

SCHEMBL23514531

N[C@@H](CSSC[C@H](N)C(=O)N1CCC(N2CCCC2)CC1)C(=O)N1CCC(N2CCCC2)CC1

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DPP8 Q6V1X1 1/20 0.49
CHRM1 P11229 2/20 0.46
L3MBTL3 Q96JM7 12/20 0.44
L3MBTL1 Q9Y468 10/20 0.44
MBTD1 Q05BQ5 4/20 0.44
TP53BP1 Q12888 2/20 0.44
L3MBTL4 Q8NA19 1/20 0.44
ALOX15 P16050 1/20 0.42
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23514532 1.00 DPP8 (0.49) DPP8CHRM1L3MBTL3L3MBTL1MBTD1
SCHEMBL23514441 0.94 DPP8 (0.46) DPP8CHRM1L3MBTL3L3MBTL1MBTD1
SCHEMBL23514549 0.88 PHGDH (0.46) DPP8CHRM1L3MBTL3L3MBTL1MEN1
SCHEMBL23514438 0.88 PHGDH (0.46) DPP8CHRM1L3MBTL3L3MBTL1MEN1
SCHEMBL23514436 0.87 PHGDH (0.38) DPP8CHRM1L3MBTL3L3MBTL1
SCHEMBL23514538 0.87 PHGDH (0.38) DPP8CHRM1L3MBTL3L3MBTL1
Hydrochloric Acid SCHEMBL23499910 0.86 PHGDH (0.45) DPP8CHRM1L3MBTL3L3MBTL1MEN1
Hydrochloric Acid SCHEMBL23499909 0.86 DPP8 (0.39) DPP8CHRM1
SCHEMBL15853678 0.83 DPP7 (0.41) DPP8
SCHEMBL23514432 0.82 PHGDH (0.42) CHRM1L3MBTL3L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230043330-A1 Cystine Diamide Analogs For Cystinuria RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2023-02-09 US disclosed
WO-2021119475-A1 CYSTINE DIAMIDE ANALOGS FOR CYSTINURIA RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2021-06-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230043330-A1 Cystine Diamide Analogs For Cystinuria CTH, CBS, SLC7A11 DPP8 621/4885CHRM1 3121/4885L3MBTL3 2947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.