Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | RRM1 | P23921 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | NPY4R | P50391 | 7/20 | 0.35 |
| ▸ | NPY1R | P25929 | 5/20 | 0.35 |
| ▸ | NPY2R | P49146 | 5/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27115457 | 0.93 | DPP7 (0.50) | SIRT6SIRT1DPP7RRM1GNAI3 | |
| SCHEMBL16263587 | 0.88 | SIRT6 (0.42) | SIRT6SIRT1DPP7RRM1CACNA1B | |
| SCHEMBL16263589 | 0.88 | SIRT6 (0.45) | SIRT6SIRT1DPP7RRM1CACNA1B | |
| SCHEMBL16260299 | 0.85 | SIRT6 (0.40) | SIRT6SIRT1DPP7RRM1GNAI3 | |
| SCHEMBL16263592 | 0.84 | SIRT6 (0.39) | SIRT6SIRT1DPP7RRM1CACNA1B | |
| SCHEMBL16263588 | 0.84 | DNM1 (0.36) | SIRT6SIRT1CACNA1BNPY4RNPY1R | |
| SCHEMBL16656681 | 0.84 | SIRT6 (0.35) | SIRT6SIRT1CACNA1BNPY4RNPY1R | |
| SCHEMBL25677222 | 0.82 | CACNA1B (0.36) | SIRT6SIRT1CACNA1BNPY4RNPY1R | |
| SCHEMBL8120411 | 0.82 | NPY4R (0.41) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL26429269 | 0.82 | NPY4R (0.41) | NPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210181206-A1 | Development of a Novel Mass Spectrometry-Based Method for Simultaneous Qualitative and Quantitative Protein Citrullination Analysis of Complex Biological Samples | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2021-06-17 | — | — | US | disclosed |