SCHEMBL23515596

SCHEMBL23515596

CC1(C)c2cc3c(cc2-c2sc(/C=C4\C(=O)c5ccccc5C4=C(C#N)C#N)cc21)C(C)(C)c1cc(/C=C2\C(=O)c4ccccc4C2=C(C#N)C#N)sc1-3

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.37
ALDH1A1 P00352 6/20 0.37
MAPT P10636 5/20 0.37
NPSR1 Q6W5P4 3/20 0.37
HPGD P15428 2/20 0.37
THRB P10828 1/20 0.37
RECQL P46063 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
HTT P42858 1/20 0.36
MEN1 O00255 3/20 0.34
PKM P14618 1/20 0.34
NPC1 O15118 1/20 0.31
CRHBP P24387 1/20 0.31
RAB9A P51151 1/20 0.31
CRHR2 Q13324 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
MITF O75030 1/20 0.31
LMNA P02545 1/20 0.31
PLA2G1B P04054 1/20 0.31
ATG4B Q9Y4P1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22382799 0.88 KMT2A (0.36) KMT2AALDH1A1MAPTNPSR1HPGD
SCHEMBL21155801 0.85 KMT2A (0.34) KMT2AALDH1A1MAPTNPSR1HPGD
SCHEMBL23515597 0.84 KMT2A (0.36) KMT2AALDH1A1MAPTNPSR1HPGD
SCHEMBL20850220 0.83 ALDH1A1 (0.31) KMT2AALDH1A1MAPTNPSR1HPGD
SCHEMBL24396451 0.83 MAPT (0.37) KMT2AALDH1A1MAPTNPSR1HPGD
SCHEMBL22382787 0.83 KMT2A (0.34) KMT2AALDH1A1MAPTNPSR1HPGD
SCHEMBL24402426 0.82 KMT2A (0.39) KMT2AALDH1A1MAPTNPSR1HPGD
SCHEMBL19803827 0.81 ALDH1A1 (0.32) KMT2AALDH1A1MAPTNPSR1HPGD
SCHEMBL31124703 0.81 ALDH1A1 (0.32) KMT2AALDH1A1MAPTNPSR1HPGD
SCHEMBL22382788 0.81 KMT2A (0.34) KMT2AALDH1A1MAPTNPSR1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022098917-A1 PHOTOACTIVE COMPOUNDS FOR VAPOR DEPOSITED ORGANIC PHOTOVOLTAIC DEVICES UBIQUITOUS ENERGY, INC. (US) 2022-05-12 WO disclosed
US-20220149298-A1 PHOTOACTIVE COMPOUNDS FOR VAPOR DEPOSITED ORGANIC PHOTOVOLTAIC DEVICES UBIQUITOUS ENERGY, INC. (US) 2022-05-12 US disclosed
US-20220135587-A1 PHOTOACTIVE COMPOUNDS FOR VAPOR DEPOSITED ORGANIC PHOTOVOLTAIC DEVICES UBIQUITOUS ENERGY, INC. (US) 2022-05-05 US disclosed
US-20220140266-A1 PHOTOACTIVE COMPOUNDS FOR VAPOR DEPOSITED ORGANIC PHOTOVOLTAIC DEVICES UBIQUITOUS ENERGY, INC. (US) 2022-05-05 US disclosed
US-11152581-B2 Visibly transparent, near-infrared-absorbing donor/acceptor photovoltaic devices UBIQUITOUS ENERGY, INC. (US) 2021-10-19 US disclosed
US-20210184145-A1 VISIBLY TRANSPARENT PHOTOACTIVE COMPOUNDS FOR NEAR-INFRARED-ABSORBING PHOTOVOLTAIC DEVICES UBIQUITOUS ENERGY, INC. (US) 2021-06-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220140266-A1 PHOTOACTIVE COMPOUNDS FOR VAPOR DEPOSITED ORGANIC PHOTOVOLTAIC DEVICES VIM, ALDH1A2, ICAM1 KMT2A 1770/4885ALDH1A1 30/4885MAPT 306/4885
US-20220149298-A1 PHOTOACTIVE COMPOUNDS FOR VAPOR DEPOSITED ORGANIC PHOTOVOLTAIC DEVICES VIM, ALDH1A2, ICAM1 KMT2A 1770/4885ALDH1A1 30/4885MAPT 306/4885
US-20220135587-A1 PHOTOACTIVE COMPOUNDS FOR VAPOR DEPOSITED ORGANIC PHOTOVOLTAIC DEVICES VIM, ALDH1A2, ICAM1 KMT2A 1770/4885ALDH1A1 30/4885MAPT 306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.