Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 7/20 | 0.46 |
| ▸ | BRD4 | O60885 | 6/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5118106 | 0.79 | CA2 (0.51) | PARP1TRPV1CREBBPBRD4ALOX5 | |
| SCHEMBL17673195 | 0.78 | CREBBP (0.72) | CREBBPBRD4 | |
| SCHEMBL5672928 | 0.78 | CREBBP (0.60) | PARP1TRPV1CREBBPBRD4BRPF1 | |
| SCHEMBL31402329 | 0.78 | CREBBP (0.60) | PARP1TRPV1CREBBPBRD4BRPF1 | |
| SCHEMBL7281859 | 0.77 | PARP1 (0.39) | PARP1TRPV1CREBBP | |
| SCHEMBL7281995 | 0.77 | DYRK1A (0.41) | PARP1TRPV1 | |
| SCHEMBL18128151 | 0.76 | PARP1 (0.56) | PARP1TRPV1CREBBPBRD4BRPF1 | |
| SCHEMBL20983200 | 0.76 | PARP1 (0.56) | PARP1TRPV1CREBBPBRD4BRPF1 | |
| SCHEMBL3593519 | 0.76 | PARP1 (0.56) | PARP1TRPV1CREBBPBRD4BRPF1 | |
| SCHEMBL12540763 | 0.76 | PARP1 (0.56) | PARP1TRPV1CREBBPBRD4BRPF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8008292-B2 | Condensed benzamide compounds and inhibitors of vanilloid receptor subtype 1 (VR1) activity | JAPAN TOBACCO INC. (JP) | 2011-08-30 | — | — | US | disclosed |
| EP-0313393-A2 | Benzoxazine compounds and pharmaceutical use thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-04-26 | — | — | EP | disclosed |