Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 5/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288542 | 0.85 | SERPINH1 (0.41) | PARP1TRPV1 | |
| SCHEMBL7281859 | 0.83 | PARP1 (0.39) | PARP1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7288322 | 0.82 | HSD17B10 (0.42) | DYRK1APARP1HSD17B10 | |
| SCHEMBL5671638 | 0.80 | PARP1 (0.44) | PARP1TRPV1 | |
| SCHEMBL20138195 | 0.78 | PARP1 (0.41) | PARP1TRPV1 | |
| SCHEMBL20138193 | 0.78 | PARP1 (0.41) | PARP1TRPV1 | |
| SCHEMBL2351573 | 0.77 | PARP1 (0.51) | PARP1TRPV1 | |
| SCHEMBL7289440 | 0.73 | HTR3A (0.58) | CYP3A4 | |
| Hydrochloric Acid SCHEMBL7279269 | 0.73 | HTR3A (0.48) | PARP1 | |
| SCHEMBL13672063 | 0.73 | PARP1 (0.38) | PARP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313393-B1 | Benzoxazine compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4892872-A | ANTIEMETICS, ANTINAUSEA | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-01-09 | — | — | US | disclosed |
| EP-0313393-A2 | Benzoxazine compounds and pharmaceutical use thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-04-26 | — | — | EP | disclosed |