Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HINT1 | P49773 | 3/20 | 0.46 |
| ▸ | PNP | P00491 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | VCP | P55072 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26794936 | 0.89 | ALDH1A1 (0.52) | ALDH1A1LMNAALBMAPK1POLB | |
| SCHEMBL22523989 | 0.89 | ALDH1A1 (0.52) | ALDH1A1LMNAALBMAPK1POLB | |
| SCHEMBL18520392 | 0.89 | ALDH1A1 (0.52) | ALDH1A1LMNAALBMAPK1POLB | |
| SCHEMBL25057493 | 0.89 | ALDH1A1 (0.52) | ALDH1A1LMNAALBMAPK1POLB | |
| SCHEMBL25914428 | 0.87 | ALDH1A1 (0.52) | ALDH1A1LMNAALBMAPK1POLB | |
| SCHEMBL22402617 | 0.87 | ALDH1A1 (0.52) | ALDH1A1LMNAALBMAPK1POLB | |
| SCHEMBL18763358 | 0.87 | ALDH1A1 (0.52) | ALDH1A1LMNAALBMAPK1POLB | |
| SCHEMBL16144132 | 0.86 | ALDH1A1 (0.51) | ALDH1A1LMNAALBMAPK1POLB | |
| SCHEMBL24633250 | 0.85 | POLB (0.52) | ALDH1A1LMNAALBMAPK1POLB | |
| SCHEMBL16552341 | 0.85 | ALDH1A1 (0.55) | ALDH1A1LMNAALBMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021252557-A1 | RNAI COMPOSITIONS AND METHODS OF USE THEREOF FOR DELIVERY BY INHALATION | ALNYLAM PHARMACEUTICALS, INC. (US) | 2021-12-16 | — | — | WO | disclosed |
| WO-2021119226-A1 | HUMAN CHROMOSOME 9 OPEN READING FRAME 72 (C9ORF72) IRNA AGENT COMPOSITIONS AND METHODS OF USE THEREOF | ALNYLAM PHARMACEUTICALS, INC. (US) | 2021-06-17 | — | — | WO | disclosed |