SCHEMBL235172

SCHEMBL235172

CCN[Si](NC)(NC)N(CC)C1CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ADH1A P07327 2/20 0.35
ADH1C P00326 1/20 0.35
ALDH1A1 P00352 1/20 0.30
S1PR1 P21453 2/20 0.30
S1PR3 Q99500 2/20 0.30
TSHR P16473 1/20 0.30
XBP1 P17861 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL233092 0.98 ADH1C (0.32) ADH1AADH1C
SCHEMBL232352 0.80 ADH1A (0.32) ADH1AADH1C
SCHEMBL231333 0.78
SCHEMBL234196 0.76 ADH1A (0.38) ADH1AADH1CS1PR1S1PR3TSHR
SCHEMBL231381 0.76 ADH1A (0.38) ADH1AADH1C
SCHEMBL231483 0.75 ADH1A (0.36) ADH1AADH1CALDH1A1S1PR1S1PR3
SCHEMBL233786 0.73 ADH1C (0.35) ADH1AADH1C
SCHEMBL235050 0.73 ADH1C (0.35) ADH1AADH1C
SCHEMBL235877 0.72 ADH1A (0.33) ADH1AADH1C
SCHEMBL235008 0.68 ADH1A (0.34) ADH1AADH1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360190-B1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO LTD (JP) 2015-10-14 EP disclosed
US-8426537-B2 Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same TOHO TITANIUM CO., LTD. (JP) 2013-04-23 US disclosed
US-20120004378-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO., LTD (JP) 2012-01-05 US disclosed
EP-2360190-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME Toho Titanium CO., LTD. (JP) 2011-08-24 EP disclosed