Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22484141 | 0.92 | SMN1; SMN2 (0.47) | SMN1; SMN2TP53HPGDKMT2AALDH1A1 | |
| SCHEMBL18199495 | 0.86 | SMN1; SMN2 (0.66) | SMN1; SMN2TP53HPGDKMT2AALDH1A1 | |
| SCHEMBL19456620 | 0.85 | SMN1; SMN2 (0.53) | SMN1; SMN2TP53HPGDKMT2AALDH1A1 | |
| SCHEMBL18194476 | 0.84 | KMT2A (0.43) | SMN1; SMN2TP53HPGDKMT2AALDH1A1 | |
| SCHEMBL23518488 | 0.84 | MEN1 (0.52) | SMN1; SMN2HPGDKMT2AALDH1A1MEN1 | |
| SCHEMBL26159768 | 0.84 | ALDH1A1 (0.41) | SMN1; SMN2TP53HPGDKMT2AALDH1A1 | |
| SCHEMBL25837453 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2TP53HPGDKMT2AALDH1A1 | |
| SCHEMBL24489956 | 0.84 | ALDH1A1 (0.41) | SMN1; SMN2TP53HPGDKMT2AALDH1A1 | |
| SCHEMBL25837450 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2TP53HPGDKMT2AALDH1A1 | |
| SCHEMBL13616900 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2TP53HPGDKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210179665-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | PARABILIS MEDICINES, INC. | 2021-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210179665-A1 | COLLECTIONS OF PEPTIDES, PEPTIDE AGENTS, AND METHODS OF USE THEREOF | IAPP, VIP, NGLY1 | SMN1; SMN2 2559/4885TP53 63/4885HPGD 4326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.