SCHEMBL23519081

SCHEMBL23519081

Cc1cc(Cl)ccc1OC(F)(F)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.53
HTR2A P28223 1/20 0.53
HTR2C P28335 1/20 0.53
HTR2B P41595 1/20 0.53
NOTUM Q6P988 1/20 0.51
MRGPRX4 Q96LA9 2/20 0.44
NPSR1 Q6W5P4 1/20 0.44
TP53 P04637 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
HIF1A Q16665 1/20 0.43
KDM4E B2RXH2 1/20 0.43
ALOX15 P16050 1/20 0.43
ALDH1A1 P00352 1/20 0.43
ESR1 P03372 1/20 0.42
POLB P06746 1/20 0.42
ESR2 Q92731 1/20 0.42
CTDSP1 Q9GZU7 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
LMNA P02545 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11176467 0.86 TSHR (0.51) TSHRHTR2AHTR2CHTR2BMRGPRX4
SCHEMBL28363492 0.83 TSHR (0.55) TSHRHTR2AHTR2CHTR2BMRGPRX4
SCHEMBL23519094 0.83 PPARA (0.51) NOTUMMRGPRX4CYP1A2TDP1MEN1
SCHEMBL23519091 0.83 NOTUM (0.47) NOTUMMRGPRX4CYP1A2CYP2C9ALDH1A1
SCHEMBL7978183 0.82 PPARA (0.57) TSHRHTR2AHTR2CHTR2BMRGPRX4
SCHEMBL16373984 0.79 ANO1 (0.46) TSHRHTR2AHTR2CHTR2BTP53
SCHEMBL23519095 0.78 ERN1 (0.45) TSHRNOTUMTDP1GAAMEN1
SCHEMBL27339695 0.78 TSHR (0.50) TSHRHTR2AHTR2CHTR2BMRGPRX4
SCHEMBL21056074 0.77 TSHR (0.49) TSHRHTR2AHTR2CHTR2BMRGPRX4
SCHEMBL26124787 0.76 NOTUM (0.56) TSHRNOTUMNPSR1CYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210179554-A1 ONIUM SALT COMPOUND, CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-06-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210179554-A1 ONIUM SALT COMPOUND, CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS SLC6A5, LIFR, SLC6A9 TSHR 3570/4885HTR2A 4684/4885HTR2C 4724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.