Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 12/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 11/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13262294 | 0.89 | ADORA2A (0.34) | ADORA1ADORA3ADORA2AADORA2BMAPT | |
| SCHEMBL9988127 | 0.81 | KDM4E (0.36) | ADORA1ADORA3ADORA2AMAPTGPR35 | |
| SCHEMBL15071229 | 0.76 | KDM4E (0.36) | ADORA1ADORA3ADORA2AMAPTGPR35 | |
| SCHEMBL3370732 | 0.76 | KDM4E (0.36) | ADORA1ADORA3ADORA2AMAPTGPR35 | |
| SCHEMBL23047279 | 0.75 | GPR35 (0.48) | ADORA3LMNAADORA2AGPR35 | |
| SCHEMBL1494391 | 0.75 | NEK1 (0.36) | — | |
| SCHEMBL18874513 | 0.75 | PDE7A (0.37) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL3842694 | 0.74 | GPR35 (0.51) | ADORA3LMNAADORA2AGPR35 | |
| SCHEMBL995654 | 0.74 | GPR35 (0.51) | ADORA3LMNAADORA2AGPR35 | |
| SCHEMBL861104 | 0.74 | GPR35 (0.51) | ADORA3LMNAADORA2AGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9577194-B2 | Hole transport compositions and related devices and methods (I) | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-02-21 | — | — | US | disclosed |
| US-20120001127-A1 | HOLE TRANSPORT COMPOSITIONS AND RELATED DEVICES AND METHODS (I) | PLEXTRONICS, INC. | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120001127-A1 | HOLE TRANSPORT COMPOSITIONS AND RELATED DEVICES AND METHODS (I) | OCIAD2, OCIAD1, SLCO1B1 | ADORA1 927/4885ADORA3 1822/4885LMNA 1906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.