SCHEMBL2352525

SCHEMBL2352525

CCCOC(OCCC)[SiH2]OC(C)=O

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.35
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4083692 0.67
SCHEMBL784098 0.67 TSHR (0.40) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL28426312 0.67
SCHEMBL7758113 0.67
SCHEMBL705410 0.67 ALDH1A1 (0.40) ALDH1A1TSHR
SCHEMBL3033507 0.67 TSHR (0.36) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL11617859 0.66 ALDH1A1 (0.37) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL31135468 0.66 ALDH1A1 (0.37) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL2479739 0.65 TSHR (0.44) ALDH1A1LMNAHSD17B10TSHR
SCHEMBL12950160 0.65 TSHR (0.44) ALDH1A1LMNAHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1448714-B1 SYNTHESIS AND USE ALKYLALKOXYACYLOXYSILANES AND BLENDS THEREOF FOR USE AS A CROSSLINKING AGENT IN MOISTURE CURING RTV'S MOMENTIVE PERFORMANCE MAT INC (US) 2011-08-24 EP disclosed
EP-1448714-A4 SYNTHESIS AND USE ALKYLALKOXYACYLOXYSILANES AND BLENDS THEREOF FOR USE AS A CROSSLINKING AGENT IN MOISTURE CURING RTV'S GEN ELECTRIC (US) 2007-04-04 EP disclosed
EP-1448714-A1 SYNTHESIS AND USE ALKYLALKOXYACYLOXYSILANES AND BLENDS THEREOF FOR USE AS A CROSSLINKING AGENT IN MOISTURE CURING RTV'S General Electronic Company (US) 2004-08-25 EP disclosed
US-6737494-B2 POLYSILOXANE USING ORGANTIN POLYMERIZATION CALALYSTS GENERAL ELECTRIC COMPANY 2004-05-18 US disclosed
WO-2003042304-A1 SYNTHESIS AND USE OF ALKYLALKOXY ACYLOXYSILANES AND BLENDS THEREOF FOR USE AS A CROSSLINKING AGENT IN MOISTURE CURING RTV'S GENERAL ELECTRIC COMPANY (US) 2003-05-22 WO disclosed
US-20030092861-A1 Synthesis and use of alkylalkoxyacyloxysilanes and blends thereof for use as a crosslinking agent in moisture curing RTV'S GENERAL ELECTRIC COMPANY 2003-05-15 US disclosed