SCHEMBL2352541

SCHEMBL2352541

O=C(O)NC(CS)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.67
MAPT P10636 1/20 0.67
THRB P10828 1/20 0.67
ALOX15 P16050 1/20 0.67
NFKB1 P19838 1/20 0.67
PTGS2 P35354 1/20 0.67
THPO P40225 1/20 0.67
RECQL P46063 1/20 0.67
BLM P54132 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
ACE P12821 1/20 0.59
FOLH1 Q04609 4/20 0.55
CA1 P00915 4/20 0.43
CA2 P00918 4/20 0.43
FNTA P49354 2/20 0.40
FNTB P49356 2/20 0.40
PTGS1 P23219 1/20 0.40
SLC7A11 Q9UPY5 1/20 0.40
NAALAD2 Q9Y3Q0 3/20 0.38
RIMKLA Q8IXN7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2352537 1.00 KDM4E (0.67) KDM4EMAPTTHRBALOX15NFKB1
Hydrochloric Acid SCHEMBL28494459 0.97 KDM4E (0.64) KDM4EMAPTTHRBALOX15NFKB1
Hydrochloric Acid SCHEMBL28494458 0.97 KDM4E (0.64) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL4984856 0.84 KDM4E (0.67) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL1289325 0.80 KDM4E (0.61) KDM4EMAPTTHRBALOX15NFKB1
Acetylcysteine SCHEMBL5292 0.80 MAPT (1.00) KDM4EMAPTTHRBALOX15NFKB1
Acetylcysteine SCHEMBL5291 0.80 MAPT (1.00) KDM4EMAPTTHRBALOX15NFKB1
Acetylcysteine SCHEMBL3688241 0.80 MAPT (1.00) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL4990899 0.80 KDM4E (0.61) KDM4EMAPTTHRBALOX15NFKB1
Acetylcysteine SCHEMBL149212 0.80 MAPT (1.00) KDM4EMAPTTHRBALOX15NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114615997-A Pharmaceutical compositions comprising cannabinoids 黑鹰有限合伙公司 2022-06-10 CN claimed
EP-3952670-A1 A HIGHLY AVAILABLE POWDER COMPOSITION CONTAINING RED RICE Pharmanutrition R&D S.r.l. (IT) 2022-02-16 EP claimed
CN-112321579-A Salts of 2-amino-1-hydroxyethyl-8-hydroxyquinolin-2 (1H) -one derivatives 阿尔米雷尔有限公司 2021-02-05 CN claimed
WO-2020208404-A1 A HIGHLY AVAILABLE POWDER COMPOSITION CONTAINING RED RICE Pharmanutrition R&D S.r.l. (IT) 2020-10-15 WO claimed
CN-106456781-B Hydroalcoholic system for nail treatment 圣地亚哥-德孔波斯特拉大学 2020-07-10 CN claimed
US-20250319050-A1 PHARMACEUTICAL FORMULATION RB HEALTH US LLC (US) 2025-10-16 US disclosed
CN-113365513-B Compositions and methods for treating lung G·E·霍格 2025-04-25 CN disclosed
US-12257218-B2 Pharmaceutical formulation RB HEALTH (US) LLC (US) 2025-03-25 US disclosed
CN-119212693-A Combination of taurine glycol and sodium phenylbutyrate for the treatment of amyotrophic lateral sclerosis 艾米利克斯制药公司 2024-12-27 CN disclosed
CN-119156207-A Methods and compositions for treating amyotrophic lateral sclerosis 艾米利克斯制药公司 2024-12-17 CN disclosed
CN-119136793-A Bile acids and phenylbutyric acid with CYP P450 or transporter substrates for the treatment of amyotrophic lateral sclerosis 艾米利克斯制药公司 2024-12-13 CN disclosed
CN-118949048-A Composition of bile acid and phenylbutyric acid compound 艾米利克斯制药公司 2024-11-15 CN disclosed
US-20170100355-A1 PHARMACEUTICAL FORMULATION RB HEALTH (US) LLC 2017-04-13 US disclosed
EP-2360195-B1 PHOTO-CURING MATERIAL MANUFACTURING METHOD, AND PHOTO-CURING MATERIAL AND ARTICLE ASAHI GLASS CO LTD (JP) 2013-02-20 EP disclosed
US-8207242-B2 Process for producing photocurable material, photocurable material and article ASAHI GLASS COMPANY, LIMITED (JP) 2012-06-26 US disclosed
US-20110237703-A1 PROCESS FOR PRODUCING PHOTOCURABLE MATERIAL, PHOTOCURABLE MATERIAL AND ARTICLE ASAHI GLASS COMPANY, LIMITED (JP) 2011-09-29 US disclosed
EP-2360195-A1 PHOTO-CURING MATERIAL MANUFACTURING METHOD, AND PHOTO-CURING MATERIAL AND ARTICLE Asahi Glass Company Limited (JP) 2011-08-24 EP disclosed
US-7329536-B2 Piezoimmunosensor OAKLAND UNIVERSITY (US) 2008-02-12 US disclosed
WO-2005001421-A2 IMPROVED PIEZOIMMUNOSENSOR OAKLAND UNIVERSITY (US) 2005-01-06 WO disclosed
US-20050003560-A1 Piezoimmunosensor OAKLAND UNIVESITY (US) 2005-01-06 US disclosed