Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | THPO | P40225 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.57 |
| ▸ | ACE | P12821 | 3/20 | 0.55 |
| ▸ | FNTA | P49354 | 5/20 | 0.53 |
| ▸ | FNTB | P49356 | 5/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.47 |
| ▸ | GNPAT | O15228 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29936413 | 0.94 | FOLH1 (0.61) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL929193 | 0.91 | KDM4E (0.57) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL8655066 | 0.87 | KDM4E (0.53) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL4321775 | 0.87 | KDM4E (0.59) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL2350309 | 0.87 | KDM4E (0.59) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL8655062 | 0.87 | KDM4E (0.53) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL929531 | 0.87 | KDM4E (0.53) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL2350303 | 0.87 | KDM4E (0.59) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL9837855 | 0.87 | KDM4E (0.53) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL8861972 | 0.86 | KDM4E (0.61) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080138309-A1 | Use Of Aminodithiol As A Reducing Agent For Hair Perming | L'OREAL S.A. (FR) | 2008-06-12 | — | — | US | claimed |
| US-20080138309-A1 | Use Of Aminodithiol As A Reducing Agent For Hair Perming | L'OREAL S.A. (FR) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080138309-A1 | Use Of Aminodithiol As A Reducing Agent For Hair Perming | AASDHPPT, BHMT2, ALAD | KDM4E 1902/4885MAPT 1421/4885THRB 3230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.