SCHEMBL23525606

SCHEMBL23525606

Cc1ccc(Br)cc1-c1ccccn1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 7/20 0.47
▸ NPC1 O15118 5/20 0.47
▸ GABRA1 P14867 1/20 0.46
▸ GABRA5 P31644 1/20 0.46
▸ GABRA3 P34903 1/20 0.46
▸ GABRA2 P47869 1/20 0.46
▸ GABRB2 P47870 1/20 0.46
▸ LMNA P02545 3/20 0.45
▸ METAP1 P53582 2/20 0.45
▸ CCR1 P32246 2/20 0.45
▸ CCR5 P51681 2/20 0.45
▸ CCR8 P51685 2/20 0.45
▸ CYP1A2 P05177 2/20 0.45
▸ POLB P06746 1/20 0.45
▸ BLM P54132 1/20 0.45
▸ HIF1A Q16665 1/20 0.45
▸ DOHH Q9BU89 1/20 0.45
▸ P4HTM Q9NXG6 1/20 0.45
▸ ADRA1A P35348 1/20 0.45
▸ RAB9A P51151 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30610286 1.00 KDM4E (0.47) KDM4ENPC1GABRA1GABRA5GABRA3
SCHEMBL30610287 1.00 KDM4E (0.47) KDM4ENPC1GABRA1GABRA5GABRA3
SCHEMBL31517097 0.84 CCR1 (0.46) KDM4ENPC1GABRA1GABRA5GABRA3
SCHEMBL28008724 0.83 KDM4E (0.50) KDM4ENPC1GABRA1GABRA5GABRA3
SCHEMBL30610288 0.82 NPC1 (0.47) KDM4ENPC1LMNAMETAP1CCR1
SCHEMBL12203857 0.82 NPC1 (0.47) KDM4ENPC1LMNAMETAP1CCR1
SCHEMBL16806017 0.81 KDM4E (0.50) KDM4ENPC1LMNAMETAP1CCR1
SCHEMBL17427076 0.81 KDM4E (0.57) KDM4ENPC1LMNAMETAP1CCR1
SCHEMBL21022955 0.80 NPC1 (0.49) KDM4ENPC1LMNAMETAP1CCR1
SCHEMBL30776779 0.79 KDM4E (0.55) KDM4ENPC1LMNAMETAP1CCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12120945-B2 Display and lighting devices comprising phosphorescent excimers with preferred molecular orientation as monochromatic emitters ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2024-10-15 — — US disclosed
CN-117279468-A Phosphorescent excimer with preferred molecular orientation as monochromatic emitter for display and illumination applications 李健 2023-12-22 — — CN disclosed
CN-111527615-B Phosphorescent excimer with preferred molecular orientation as monochromatic emitter for display and illumination applications 李健 2023-10-17 — — CN disclosed
US-20230247897-A1 Phosphorescent Excimers with Preferred Molecular Orientation as Monochromatic Emitters for Display And Lighting Applications UNITED STATES DEPARTMENT OF ENERGY 2023-08-03 — — US disclosed
US-20230247897-A1 Phosphorescent Excimers with Preferred Molecular Orientation as Monochromatic Emitters for Display And Lighting Applications UNITED STATES DEPARTMENT OF ENERGY 2023-08-03 — — US disclosed
US-20230247897-A1 Phosphorescent Excimers with Preferred Molecular Orientation as Monochromatic Emitters for Display And Lighting Applications UNITED STATES DEPARTMENT OF ENERGY 2023-08-03 — — US disclosed
US-11594688-B2 Display and lighting devices comprising phosphorescent excimers with preferred molecular orientation as monochromatic emitters ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2023-02-28 — — US disclosed
US-20210193936-A1 PHOSPHORESCENT EXCIMERS WITH PREFERRED MOLECULAR ORIENTATION AS MONOCHROMATIC EMITTERS FOR DISPLAY AND LIGHTING APPLICATIONS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2021-06-24 — — US disclosed
CN-111527615-A Phosphorescent excimer molecules with preferred molecular orientation as monochromatic emitters for display and lighting applications 李健 2020-08-11 — — CN disclosed
CN-101010339-B Human glucagon-like-peptide-1 modulators and their use in treatment of diabetes and related conditions BRISTOL MYERS SQUIBB CO 2011-11-09 — — CN disclosed
CN-101495502-A N-terminally modified GLP-1 receptor modulators BRISTOL MYERS SQUIBB CO (US) 2009-07-29 — — CN disclosed
CN-101282991-A N-terminally modified GLP-1 receptor modulators BRISTOL MYERS SQUIBB CO (US) 2008-10-08 — — CN disclosed
CN-101010339-A Human glucagon-like-peptide-1 modulators and their use in treatment of diabetes and related conditions BRISTOL MYERS SQUIBB CO (US) 2007-08-01 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210193936-A1 PHOSPHORESCENT EXCIMERS WITH PREFERRED MOLECULAR ORIENTATION AS MONOCHROMATIC EMITTERS FOR DISPLAY AND LIGHTING APPLICATIONS PDCD1LG2, DCX, EMC2 KDM4E 4324/4885NPC1 3646/4885GABRA1 3706/4885
US-11594688-B2 Display and lighting devices comprising phosphorescent excimers with preferred molecular orientation as monochromatic emitters PDCD1LG2, EML4, EMC3 KDM4E 4181/4885NPC1 3725/4885GABRA1 3580/4885
US-12120945-B2 Display and lighting devices comprising phosphorescent excimers with preferred molecular orientation as monochromatic emitters PDCD1LG2, EML4, EMC3 KDM4E 4181/4885NPC1 3725/4885GABRA1 3580/4885
US-20230247897-A1 Phosphorescent Excimers with Preferred Molecular Orientation as Monochromatic Emitters for Display And Lighting Applications PDCD1LG2, DCX, EMC2 KDM4E 4324/4885NPC1 3646/4885GABRA1 3706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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