Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.69 |
| ▸ | HPGD | P15428 | 6/20 | 0.69 |
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | KDR | P35968 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.68 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.68 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.68 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.68 |
| ▸ | PDE4A | P27815 | 1/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3628199 | 0.89 | ALDH1A1 (0.66) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL28188089 | 0.88 | ALDH1A1 (0.64) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| Aspirin SCHEMBL27414704 | 0.86 | KDM4E (0.67) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL3278617 | 0.85 | HSD17B10 (0.73) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| Aspirin SCHEMBL11799149 | 0.85 | KDM4E (0.65) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| Salsalate SCHEMBL15562 | 0.82 | HSD17B10 (1.00) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| Salsalate SCHEMBL29362887 | 0.82 | HSD17B10 (1.00) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| Salsalate SCHEMBL2025628 | 0.82 | HSD17B10 (1.00) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL3773764 | 0.82 | HSD17B10 (0.69) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL14577689 | 0.82 | MAPT (0.64) | KDM4EALDH1A1HSD17B10HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361620-A1 | Use of aminosalicylates in diarrhoea-predominant irritable bowel syndrome | PHARMATEL (R&D) PTY LIMITED as Trustee for the PHARMATEL (R & D) TRUST (AU) | 2011-08-31 | — | — | EP | disclosed |