Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.66 |
| ▸ | KDR | P35968 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.65 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.65 |
| ▸ | PDE4A | P27815 | 1/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28188089 | 0.98 | ALDH1A1 (0.64) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| SCHEMBL2352963 | 0.89 | KDM4E (0.69) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| SCHEMBL831732 | 0.89 | KDM4E (0.64) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| SCHEMBL3628204 | 0.85 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| SCHEMBL29015053 | 0.82 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL30337954 | 0.80 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL29450213 | 0.80 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL2262 | 0.80 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| Aminosalicylic Acid SCHEMBL3333393 | 0.80 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTCYP3A4GAA | |
| SCHEMBL9949353 | 0.80 | ALDH1A1 (0.66) | ALDH1A1KDM4EMAPTCYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150243-A2 | COMPOSITIONS AND METHODS FOR ENHANCING ACTIVE AGENT ABSORPTION | Nexus Pharma, Inc. (US) | 2010-02-10 | — | — | EP | disclosed |
| WO-2008144690-A2 | COMPOSITIONS AND METHODS FOR ENHANCING ACTIVE AGENT ABSORPTION | NEXUS PHARMA, INC. (US) | 2008-11-27 | — | — | WO | disclosed |
| US-7183269-B2 | Synergistic compositions for the selective control of tumor tissue | KREUTZ WERNER | 2007-02-27 | — | — | US | disclosed |
| US-20040147493-A1 | Synergistic compositions for the selective control of tumor tissue | KREUTZ WERNER | 2004-07-29 | — | — | US | disclosed |
| US-6727235-B2 | Synergistic mixture comprising benzoic acid derivatives for use as anticarcinogenic agents, antitumor agents | KREUTZ WERNER (DE) | 2004-04-27 | — | — | US | disclosed |
| US-20030166621-A1 | Synergistic mixture comprising benzoic acid derivatives for use as anticarcinogenic agents, antitumor agents | KREUTZ WERNER (DE) | 2003-09-04 | — | — | US | disclosed |
| US-6525038-B1 | Synergistic composition of 5-(2,4-difluorophenyl) salicylic acid and 2-hydroxy-4-aminobenzoic acid | KREUTZ WERNER (DE) | 2003-02-25 | — | — | US | disclosed |