Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.42 |
| ▸ | LIPC | P11150 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.39 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17703914 | 0.86 | RXRA (0.47) | CES2RXRARXRBRXRGTACR1 | |
| SCHEMBL28056425 | 0.83 | GRIK1 (0.45) | GRIK1MEN1KMT2A | |
| SCHEMBL27782015 | 0.83 | GRIK1 (0.45) | GRIK1MEN1KMT2A | |
| SCHEMBL16727003 | 0.82 | NOTUM (0.55) | MRGPRX4CES2TACR1MEN1KMT2A | |
| SCHEMBL27761970 | 0.78 | RXRA (0.53) | MRGPRX4CES2RXRARXRBRXRG | |
| SCHEMBL2993355 | 0.77 | MRGPRX4 (0.51) | MRGPRX4CES2RXRARXRBRXRG | |
| SCHEMBL17897037 | 0.77 | MRGPRX4 (0.51) | MRGPRX4CES2RXRARXRBRXRG | |
| SCHEMBL4961189 | 0.76 | CYP2C19 (0.52) | TACR1CYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL23570087 | 0.76 | MRGPRX4 (0.48) | MRGPRX4CES2RXRARXRBRXRG | |
| SCHEMBL23570421 | 0.76 | TPMT (0.53) | MRGPRX4RXRARXRBCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021122645-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-06-24 | — | — | WO | disclosed |
| WO-2021122645-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-06-24 | — | — | WO | disclosed |