Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.53 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.47 |
| ▸ | GRN | P28799 | 2/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.40 |
| ▸ | SPR | P35270 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28056425 | 0.87 | GRIK1 (0.45) | TPMTGRIK1MEN1KMT2AKDM4E | |
| SCHEMBL27782015 | 0.87 | GRIK1 (0.45) | TPMTGRIK1MEN1KMT2AKDM4E | |
| SCHEMBL8979358 | 0.76 | TPMT (0.64) | TPMTHCAR1HCAR2MRGPRX4TTR | |
| SCHEMBL23531175 | 0.76 | MRGPRX4 (0.47) | GRIK1CYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL23570082 | 0.75 | TPMT (0.52) | TPMTHCAR1HCAR2MRGPRX4TTR | |
| SCHEMBL8631916 | 0.74 | ALDH1A1 (0.37) | GRNSORT1SLC6A2SLC6A4SPR | |
| SCHEMBL6954785 | 0.74 | TPMT (0.61) | TPMTHCAR1HCAR2MRGPRX4TTR | |
| SCHEMBL23365143 | 0.73 | CYP2C9 (0.52) | SLC6A2SLC6A4SPRCYP2C9CYP2C19 | |
| SCHEMBL27709068 | 0.73 | TPMT (0.59) | TPMTHCAR1HCAR2MRGPRX4TTR | |
| SCHEMBL23699 | 0.72 | TPMT (1.00) | TPMTHCAR1HCAR2TTRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021122645-A1 | PESTICIDALLY ACTIVE AZOLE-AMIDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-06-24 | — | — | WO | disclosed |