Levobetaxolol

Levobetaxolol

SCHEMBL23532

CC(C)NC[C@H](O)COc1ccc(CCOCC2CC2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRB1

The experimentally established mechanism targets of Levobetaxolol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ADRB1 known ✓ P08588 3/20 1.00
LMNA P02545 2/20 1.00
CYP2D6 P10635 2/20 1.00
MEN1 O00255 1/20 1.00
CYP1A2 P05177 1/20 1.00
CYP2C9 P11712 1/20 1.00
KMT2A Q03164 1/20 1.00
ADRB2 P07550 2/20 0.98
GAA P10253 1/20 0.98
BLM P54132 1/20 0.98
TMEM97 Q5BJF2 1/20 0.98
SIGMAR1 Q99720 1/20 0.98
NR3C1 P04150 1/20 0.68
ADRA1A P35348 1/20 0.68
CYP2J2 P51589 1/20 0.68
PDE4D Q08499 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Betaxolol SCHEMBL23530 1.00 ADRB1 (1.00) ADRB1LMNACYP2D6MEN1CYP1A2
Betaxolol SCHEMBL4997902 1.00 ADRB1 (1.00) ADRB1LMNACYP2D6MEN1CYP1A2
Betaxolol SCHEMBL23531 1.00 ADRB1 (1.00) ADRB1LMNACYP2D6MEN1CYP1A2
Betaxolol SCHEMBL6512495 1.00 ADRB1 (1.00) ADRB1LMNACYP2D6MEN1CYP1A2
Betaxolol SCHEMBL42794 0.99 LMNA (1.00) ADRB1LMNACYP2D6MEN1CYP1A2
Betaxolol SCHEMBL26664826 0.99 ADRB1 (0.98) ADRB1LMNACYP2D6MEN1CYP1A2
Levobetaxolol SCHEMBL42795 0.99 LMNA (1.00) ADRB1LMNACYP2D6MEN1CYP1A2
Betaxolol SCHEMBL26664823 0.99 ADRB1 (0.98) ADRB1LMNACYP2D6MEN1CYP1A2
Levobetaxolol SCHEMBL1649403 0.98 ADRB1 (0.96) ADRB1LMNACYP2D6MEN1CYP1A2
Betaxolol SCHEMBL613385 0.98 ADRB1 (0.96) ADRB1LMNACYP2D6MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 26154 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6335335-B1 None US claimed
WO-2026102187-A1 ENGINEERED VIRUS-LIKE PARTICLES COMPRISING A BASE EDITOR FOR THE TREATMENT OF GLAUCOMA, AND APPLICATIONS THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-15 WO claimed
EP-4739302-A2 HYALURONIC ACID BASED DRUG DELIVERY SYSTEMS Cella Therapeutics, LLC (US) 2026-05-13 EP claimed
EP-4731194-A1 MATERIALS AND METHODS FOR MITIGATING THE PRESENCE OF NITROSAMINES IN PACKAGING USING AN ACTIVE AGENT CSP Technologies, Inc. (US) 2026-04-29 EP claimed
EP-4727545-A2 COMBINATION TREATMENTS FOR DEPRESSION AND OTHER DISORDERS Neurawell Therapeutics (US) 2026-04-22 EP claimed
EP-4724839-A2 CONTACT LENSES INCLUDING MEDICAMENTS AND METHODS OF MAKING AND USING SAME INCLUDING SLOW RELEASE OF GLAUCOMA TREATING DRUGS AND COMFORT ENHANCING DRUGS Mediprint Ophthalmics Inc. (US) 2026-04-15 EP claimed
EP-4724079-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION Stealth BioTherapeutics Inc. (US) 2026-04-15 EP claimed
EP-4722714-A1 SIMULTANEOUS ANALYSIS OF FOOD-BORNE DOPING SUBSTANCES USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (VFD: VACCINE FOR FOODBORNE DOPING) Korea Institute of Science and Technology (KR) 2026-04-08 EP claimed
US-20260090984-A1 CONTACT LENSES INCLUDING MEDICAMENTS AND METHODS OF MAKING AND USING SAME INCLUDING SLOW RELEASE OF GLAUCOMA TREATING DRUGS AND COMFORT ENHANCING DRUGS MEDIPRINT OPHTHALMICS INC. (US) 2026-04-02 US claimed
US-20260076953-A1 METHODS OF DIAGNOSING AND TREATING ADHD IN BIOMARKER POSITIVE SUBJECTS THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) 2026-03-19 US claimed
WO-1987007141-A1 METHOD FOR TREATING GLAUCOMA NEW ENGLAND MEDICAL CENTER HOSPITALS, INC. (US) 1987-12-03 WO claimed
EP-0227818-A1 ANTIGLAUCOMA COMPOSITIONS. SCHERING CORP (US) 1987-07-08 EP claimed
EP-0209897-A2 Peptide enzyme inhibitors MERCK & CO. INC. (US) 1987-01-28 EP claimed
WO-1987000055-A1 ANTIGLAUCOMA COMPOSITIONS SCHERING CORPORATION (US) 1987-01-15 WO claimed
EP-0194178-A1 Pharmaceutical compositions of betaxolol and nifedipine SYNTHELABO (FR) 1986-09-10 EP claimed
EP-0163237-A2 Di- and tri-peptidal renin inhibitors MERCK & CO. INC. (US) 1985-12-04 EP claimed
EP-0157409-A2 Renin inhibitors containing 2-substituted statine MERCK & CO. INC. (US) 1985-10-09 EP claimed
EP-0156318-A2 C-terminal amide cyclic renin inhibitors containing peptide isosteres MERCK & CO. INC. (US) 1985-10-02 EP claimed
EP-0156322-A2 Renin inhibitors containing peptide isosteres MERCK & CO. INC. (US) 1985-10-02 EP claimed
EP-0129189-A2 Renin inhibitors containing a C-terminal amide cycle and compositions and combinations containing the same MERCK & CO. INC. (US) 1984-12-27 EP claimed