Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29931820 | 1.00 | ALDH1A1 (0.36) | ALDH1A1MAPTGAALMNAHTT | |
| SCHEMBL23536151 | 0.88 | ALDH1A1 (0.40) | ALDH1A1MAPTGAALMNAHTT | |
| SCHEMBL29932072 | 0.88 | ALDH1A1 (0.40) | ALDH1A1MAPTGAALMNAHTT | |
| SCHEMBL23536037 | 0.88 | ALDH1A1 (0.40) | ALDH1A1MAPTGAALMNAHTT | |
| SCHEMBL29932032 | 0.88 | ALDH1A1 (0.40) | ALDH1A1MAPTGAALMNAHTT | |
| SCHEMBL23536158 | 0.82 | GRM2 (0.32) | GRM2 | |
| SCHEMBL29931942 | 0.82 | GRM2 (0.32) | GRM2 | |
| SCHEMBL29932075 | 0.80 | ALDH1A1 (0.37) | ALDH1A1MAPTGAALMNAHTT | |
| SCHEMBL23536012 | 0.80 | ALDH1A1 (0.37) | ALDH1A1MAPTGAALMNAHTT | |
| SCHEMBL23536056 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MAPTGAALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127337-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |