Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GPR174 | Q9BXC1 | 6/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23536037 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MAPTGAALMNAHTT | |
| SCHEMBL29932032 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MAPTGAALMNAHTT | |
| SCHEMBL29932072 | 1.00 | ALDH1A1 (0.40) | ALDH1A1MAPTGAALMNAHTT | |
| SCHEMBL29931820 | 0.88 | ALDH1A1 (0.36) | ALDH1A1MAPTGAALMNAHTT | |
| SCHEMBL23536259 | 0.88 | ALDH1A1 (0.36) | ALDH1A1MAPTGAALMNAHTT | |
| SCHEMBL23536005 | 0.81 | MEN1 (0.33) | GAAKMT2AMEN1 | |
| SCHEMBL23536178 | 0.81 | MEN1 (0.33) | GAAKMT2AMEN1 | |
| SCHEMBL23536056 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MAPTGAALMNAHTT | |
| SCHEMBL23536079 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MAPTGAALMNAHTT | |
| SCHEMBL29932012 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MAPTGAALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115087440-A | TRPML modulators | 卡斯玛治疗公司 | 2022-09-20 | — | — | CN | disclosed |
| WO-2021127337-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |