Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 13/20 | 0.61 |
| ▸ | RAB9A | P51151 | 13/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.61 |
| ▸ | MAPT | P10636 | 9/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.61 |
| ▸ | MEN1 | O00255 | 8/20 | 0.61 |
| ▸ | CASP3 | P42574 | 2/20 | 0.61 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.61 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.61 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.51 |
| ▸ | RELA | Q04206 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3112891 | 0.83 | NPC1 (0.78) | IDO1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL30073965 | 0.83 | NPC1 (0.78) | IDO1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL11592408 | 0.79 | IDO1 (0.66) | IDO1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL17833027 | 0.79 | IDO1 (0.66) | IDO1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL29909885 | 0.79 | IDO1 (0.66) | IDO1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL758888 | 0.79 | IDO1 (0.66) | IDO1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9754418 | 0.79 | IDO1 (0.66) | IDO1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL11592410 | 0.79 | IDO1 (0.66) | IDO1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL1132595 | 0.79 | IDO1 (1.00) | IDO1NPC1RAB9ASMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL3130678 | 0.78 | IDO1 (0.63) | IDO1NPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103130745-B | Diaryl piperazine compounds and its medical usage | 中国人民解放军军事医学科学院毒物药物研究所 | 2017-03-15 | — | — | CN | disclosed |
| EP-2536285-A1 | SUBSTITUTED FUSED IMIDAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | High Point Pharmaceuticals, LLC (US) | 2012-12-26 | — | — | EP | disclosed |
| WO-2011103018-A1 | SUBSTITUTED FUSED IMIDAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | HIGH POINT PHARMACEUTICALS, LLC (US) | 2011-08-25 | — | — | WO | disclosed |