SCHEMBL9754418

SCHEMBL9754418

SNc1nc2ccccc2s1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.66
NPC1 O15118 13/20 0.61
RAB9A P51151 13/20 0.61
SMN1; SMN2 Q16637 10/20 0.61
MAPT P10636 8/20 0.61
KMT2A Q03164 7/20 0.61
MEN1 O00255 6/20 0.61
CASP3 P42574 1/20 0.61
SENP8 Q96LD8 1/20 0.61
SENP7 Q9BQF6 1/20 0.61
SENP6 Q9GZR1 1/20 0.61
GAA P10253 4/20 0.56
ALDH1A1 P00352 3/20 0.56
ADORA1 P30542 1/20 0.56
DYRK1A Q13627 1/20 0.56
CYP1A2 P05177 1/20 0.53
HPGD P15428 2/20 0.53
MAPK1 P28482 2/20 0.53
NFKB1 P19838 5/20 0.51
NFKB2 Q00653 5/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3112891 0.83 NPC1 (0.78) IDO1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL30073965 0.83 NPC1 (0.78) IDO1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL29909885 0.79 IDO1 (0.66) IDO1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL11592408 0.79 IDO1 (0.66) IDO1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL2353642 0.79 IDO1 (0.66) IDO1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL758888 0.79 IDO1 (0.66) IDO1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL1132595 0.79 IDO1 (1.00) IDO1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL17833027 0.79 IDO1 (0.66) IDO1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL11592410 0.79 IDO1 (0.66) IDO1NPC1RAB9ASMN1; SMN2MAPT
Hydrochloric Acid SCHEMBL3130678 0.78 IDO1 (0.63) IDO1NPC1RAB9ASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101139338-B Preparation of 2,2'-disulfo-dibenzopyrene by oxygen process based on 2-mercaptan benzothiazole ammonia salt QINGDAO TECHNOLOGY UNIVERSITY 2013-10-23 CN claimed
CN-101139338-A Preparation of 2,2-disulfo-dibenzopyrene by oxygen process based on 2-mercaptan benzothiazole ammonia salt QINGDAO TECHNOLOGY UNIVERSITY (CN) 2008-03-12 CN claimed
CN-118251316-A Pneumatic tire 株式会社普利司通 2024-06-25 CN disclosed
EP-3312160-B1 HEPATITIS B ANTIVIRAL AGENTS NOVIRA THERAPEUTICS INC (US) 2020-03-18 EP disclosed
US-9981929-B2 Method for prevention of premature polymerization NITTO BELGIUM NV (BE) 2018-05-29 US disclosed
EP-3312160-A1 HEPATITIS B ANTIVIRAL AGENTS Novira Therapeutics Inc. (US) 2018-04-25 EP disclosed
US-20170369458-A1 METHOD FOR PREVENTION OF PREMATURE POLYMERIZATION NITTO EUROPE N.V. (BE) 2017-12-28 US disclosed
US-9796693-B2 Method for prevention of premature polymerization NITTO EUROPE N.V. (BE) 2017-10-24 US disclosed
US-20160280673-A1 METHOD FOR PREVENTION OF PREMATURE POLYMERIZATION NITTO EUROPE N.V. (BE) 2016-09-29 US disclosed
EP-3072879-A1 METHOD FOR PREVENTION OF PREMATURE POLYMERIZATION NITTO EUROPE N.V (BE) 2016-09-28 EP disclosed
US-5032588-A Non-steroidal antiinflammatory ABBOTT LABORATORIES (US) 1991-07-16 US disclosed
WO-1991008744-A1 THIAZOLE LIPOXYGENASE-INHIBITING COMPOUNDS DERIVED FROM NON-STEROIDAL ANTIINFLAMMATORY CARBOXYLIC ACIDS ABBOTT LABORATORIES (US) 1991-06-27 WO disclosed
US-4271308-A FUNGICIDES ROHM AND HAAS COMPANY (US) 1981-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160280673-A1 METHOD FOR PREVENTION OF PREMATURE POLYMERIZATION PGF, TTPA, MLN IDO1 4105/4885NPC1 322/4885RAB9A 4435/4885
US-20170369458-A1 METHOD FOR PREVENTION OF PREMATURE POLYMERIZATION PGF, TTPA, MLN IDO1 4105/4885NPC1 322/4885RAB9A 4435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.