Sugi Predict

Sugi Predict / Compounds / SCHEMBL1132595

SCHEMBL1132595

SCHEMBL1132595

NNc1nc2ccccc2s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ IDO1 P14902 2/20 1.00
▸ MAPT P10636 10/20 0.61
▸ NPC1 O15118 10/20 0.61
▸ RAB9A P51151 10/20 0.61
▸ SMN1; SMN2 Q16637 9/20 0.61
▸ MEN1 O00255 7/20 0.61
▸ KMT2A Q03164 7/20 0.61
▸ CASP3 P42574 1/20 0.61
▸ SENP8 Q96LD8 1/20 0.61
▸ SENP7 Q9BQF6 1/20 0.61
▸ SENP6 Q9GZR1 1/20 0.61
▸ ALDH1A1 P00352 6/20 0.61
▸ GAA P10253 6/20 0.61
▸ LMNA P02545 4/20 0.58
▸ KDM4E B2RXH2 3/20 0.58
▸ PKM P14618 3/20 0.58
▸ MAPK1 P28482 3/20 0.58
▸ ALOX12 P18054 2/20 0.58
▸ TDP1 Q9NUW8 2/20 0.58
▸ GFER P55789 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30073965 0.83 NPC1 (0.78) IDO1MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL3112891 0.83 NPC1 (0.78) IDO1MAPTNPC1RAB9ASMN1; SMN2
Coumarin SCHEMBL28241813 0.80 IDO1 (0.63) IDO1MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL11592408 0.79 IDO1 (0.66) IDO1MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL9754418 0.79 IDO1 (0.66) IDO1MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL758888 0.79 IDO1 (0.66) IDO1MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL17833027 0.79 IDO1 (0.66) IDO1MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL11592410 0.79 IDO1 (0.66) IDO1MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL29909885 0.79 IDO1 (0.66) IDO1MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL28125161 0.79 IDO1 (0.66) IDO1MAPTNPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 915 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3440070-B1 MDR-REVERSING 8-HYDROXY-QUINOLINE DERIVATIVES MTA TERMESZETTUDOMANYI KUTATOKOEZPONT (HU) 2024-10-30 — — EP claimed
CN-118534063-A Kit and method for rapidly detecting heavy metal mercury silver in grains 南京财经大学 2024-08-23 — — CN claimed
CN-114791423-B Preparation method and application of fluorescence sensor for glyphosate detection 哈尔滨理工大学 2024-08-09 — — CN claimed
US-20240216316-A1 DIHOMO-GAMMA LINOLENIC ACID (DGLA) IS A NOVEL SENOLYTIC BUCK INST RES AGING (US) 2024-07-04 — — US claimed
CN-118255758-A Novel dimer-induced AIE intelligent material and application thereof 广东医科大学 2024-06-28 — — CN claimed
CN-115583944-B Preparation method and application of benzothiazole derivative 哈尔滨理工大学 2024-06-21 — — CN claimed
CN-118184646-A Pyrazoline derivative light conversion material for photovoltaic adhesive film, and preparation method and application thereof 苏州弘道新材料有限公司 2024-06-14 — — CN claimed
CN-118048155-A Titanium nitride etching liquid, preparation method, application and cleaning method thereof 浙江奥首材料科技有限公司 2024-05-17 — — CN claimed
US-20240115563-A1 Treatment of a Senescence-Associated Ocular Disease or Disorder Using a Bcl-xL Selective Inhibitor UNITY BIOTECHNOLOGY, INC. 2024-04-11 — — US claimed
CN-117466918-A 2-bipyridyl ketone benzothiazole hydrazone copper complex-apoferritin nanoparticle and preparation method and application thereof 广西科技师范学院 2024-01-30 — — CN claimed
WO-2002034265-A1 USE OF 2-HYDRAZINO-1,3-THIAZOLES AS ANTIOXIDANTS HAARMANN & REIMER GMBH (DE) 2002-05-02 — — WO claimed
WO-2001062208-A2 TOPICAL COSMETIC AGENTS CONTAINING 2-HYDRAZINO-1,3-HETEROAZOLES HAARMANN & REIMER GMBH (DE) 2001-08-30 — — WO claimed
US-6197722-B1 STORAGE STABILITY; IMAGES HAVING COLOR SATURATION AND COLOR GAMUT; INK JET PRINTING; NONSMEARING EASTMAN KODAK COMPANY 2001-03-06 — — US claimed
US-6143693-A STORAGE STABILITY; ENABLES TO PRODUCE IMAGES HAVING COLOR SATURATION AND COLOR GAMUT, RESISTANCE TO DARK AND LIGHT FADE, RESISTANCE TO IMAGE SMEAR AND RUB-OFF, MOISTURE AND HUMIDITY RESISTANCE EASTMAN KODAK COMPANY (US) 2000-11-07 — — US claimed
EP-0433977-B1 Method for optical measurement of bilirubin and reagent therefor NIPPON SHOJI KK (JP) 1995-05-31 — — EP claimed
US-5262304-A Reacting with a zinc compound, bilirubin oxidase in a buffer and a coloring agent NIPPON SHOJI KABUSHIKI KAISHA (JP) 1993-11-16 — — US claimed
EP-0433977-A2 Method for optical measurement of bilirubin and reagent therefor NIPPON SHOJI KABUSHIKI KAISHA (JP) 1991-06-26 — — EP claimed
US-4418037-A PYROGALLOL DERIVATIVE STORAGE STABILIZER FUJI PHOTO FILM CO., LTD. (JP) 1983-11-29 — — US claimed
EP-0043013-B1 PROCESS FOR THE PREPARATION OF 2-CHLORO-BENZOTHIAZOLES HOECHST AKTIENGESELLSCHAFT (DE) 1983-06-01 — — EP claimed
US-3960677-A CARBOXY TERMINATED ANIONIC WETTING AGENT, FURAN, THIOPHENE, OR THIAZOLE BRIGHTNER THE HARSHAW CHEMICAL COMPANY (US) 1976-06-01 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240216316-A1 DIHOMO-GAMMA LINOLENIC ACID (DGLA) IS A NOVEL SENOLYTIC DAGLA, DAGLB, MGLL IDO1 2519/4885MAPT 4494/4885NPC1 2247/4885
US-20240115563-A1 Treatment of a Senescence-Associated Ocular Disease or Disorder Using a Bcl-xL Selective Inhibitor BCL2L1, BCL2L13, BCL2 IDO1 1461/4885MAPT 2192/4885NPC1 4755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.