N,N'-Dinitrosopiperazine

N,N'-Dinitrosopiperazine

SCHEMBL2353649

O=NN1CCN(N=O)CC1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3262072 1.00
SCHEMBL11507080 0.84
SCHEMBL606668 0.84
SCHEMBL10846066 0.84
SCHEMBL18574286 0.83
SCHEMBL605035 0.81
SCHEMBL1578024 0.81
SCHEMBL105009 0.81 ALDH1A1 (0.32)
SCHEMBL95309 0.78
SCHEMBL1700300 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117328068-A Tungsten plug chemical mechanical polishing solution for reducing dishing and application thereof 万华化学集团电子材料有限公司 2024-01-02 CN claimed
CN-117159215-A Method for constructing tree shrew nasopharyngeal carcinoma animal model based on combination of 1,4-dinitroso piperazine and EB virus 广西医科大学第一附属医院 2023-12-05 CN claimed
CN-115963202-A Method for determining nitrosamine genotoxic impurities by using gas chromatography triple quadrupole mass spectrometry 上海合全药物研发有限公司 2023-04-14 CN claimed
CN-203990151-U A kind of cleaner for ocean platform kitchen JIANGSU MARITIME INST 2014-12-10 CN claimed
WO-2013106831-A1 THERMAL DESTRUCTION OF NITROSAMINE IN CO2 CAPTURE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2013-07-18 WO claimed
US-4535154-A ONE-STEP USING POTASSIUM HYDROXIDE AND A NICKEL-ALUMINUM CATALYST UNITED STATES OF AMERICA (US) 1985-08-13 US claimed
US-4053317-A N-NITROSO COMPOUND, PHOTOPOLYMERIZABLE COMPOUND TEIJIN LIMITED (JA) 1977-10-11 US claimed
CN-118978495-A Preparation method of 1-amino-4-cyclopentyl piperazine 辽宁友之泰医药科技有限公司 2024-11-19 CN disclosed
CN-117899041-A Astragaloside effervescent tablet and preparation process and application thereof 浙江省肿瘤医院 2024-04-19 CN disclosed
CN-115650940-B Compounds isolated from Rheum emodi and their use in the treatment of neurological disorders 中国医学科学院药用植物研究所 2024-03-29 CN disclosed
CN-117328068-A Tungsten plug chemical mechanical polishing solution for reducing dishing and application thereof 万华化学集团电子材料有限公司 2024-01-02 CN disclosed
CN-117159215-A Method for constructing tree shrew nasopharyngeal carcinoma animal model based on combination of 1,4-dinitroso piperazine and EB virus 广西医科大学第一附属医院 2023-12-05 CN disclosed
CN-117159215-A Method for constructing tree shrew nasopharyngeal carcinoma animal model based on combination of 1,4-dinitroso piperazine and EB virus 广西医科大学第一附属医院 2023-12-05 CN disclosed
EP-0835233-A1 COMPOSITION AND METHOD FOR STABILIZING RADIOLABELED ORGANIC COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-04-15 EP disclosed
US-5738836-A Composition for stabilizing radiolabeled organic compounds E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-04-14 US disclosed
WO-1997001520-A1 COMPOSITION AND METHOD FOR STABILIZING RADIOLABELED ORGANIC COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-01-16 WO disclosed
US-5096808-A Detecting presence of antibodies specific to DNA-adducts of polycyclic aromatic hydrocarbons in human serum, correlating presence of antibodies to current or past to exposure to genotixic agents THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1992-03-17 US disclosed
US-4794074-A USING ADDUCT OF 7B,8A-DIHYDROXY-9A,10A-EPOXY-7,8,9,10-TETRAHYDROBENZO(A)PYRENE AND DEOXYRIBONUCLEIC ACID THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1988-12-27 US disclosed
US-4411881-A Composition and method for stabilizing radiolabeled compounds using thiocarbonylated diethylenetriamines NEW ENGLAND NUCLEAR CORPORATION (US) 1983-10-25 US disclosed
US-4053317-A N-NITROSO COMPOUND, PHOTOPOLYMERIZABLE COMPOUND TEIJIN LIMITED (JA) 1977-10-11 US disclosed