Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16648719 | 0.82 | GRM4 (0.54) | GRM4 | |
| SCHEMBL23570337 | 0.81 | HTR2C (0.51) | GRM4 | |
| SCHEMBL23570187 | 0.78 | MAPK1 (0.44) | GRM4LRRK2 | |
| SCHEMBL30600701 | 0.75 | GRM4 (0.52) | GRM4 | |
| SCHEMBL24244004 | 0.74 | GRM4 (1.00) | GRM4 | |
| SCHEMBL30417327 | 0.72 | DRD4 (0.44) | GRM4 | |
| SCHEMBL30748575 | 0.71 | GRM4 (0.42) | GRM4 | |
| SCHEMBL12327159 | 0.71 | PIM1 (0.43) | GRM4LRRK2 | |
| SCHEMBL22597907 | 0.71 | GRIN2D (0.51) | GRM4 | |
| SCHEMBL30417099 | 0.71 | HSD11B1 (0.49) | GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127333-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |