Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 3/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30600701 | 0.87 | GRM4 (0.52) | GRM4PDE10AHTR2AHTR2CSLC6A4 | |
| SCHEMBL26650487 | 0.78 | GRM4 (0.43) | GRM4PDE10AMTORSCN10AHRH4 | |
| SCHEMBL30600597 | 0.78 | HTR2A (0.63) | HTR2AHTR2CSLC6A4KDM4EGMNN | |
| SCHEMBL30417327 | 0.72 | DRD4 (0.44) | GRM4PDE10AMAPTSCN10AMAOB | |
| SCHEMBL23536563 | 0.71 | GRM4 (0.57) | GRM4 | |
| SCHEMBL30417104 | 0.71 | HSD11B1 (0.48) | TRPV1 | |
| SCHEMBL22597907 | 0.71 | GRIN2D (0.51) | GRM4PDE10AKDM4ESCN10ATRPV1 | |
| SCHEMBL30417099 | 0.71 | HSD11B1 (0.49) | GRM4PDE10ASCN10ATRPV1 | |
| SCHEMBL26646371 | 0.71 | SCN10A (0.46) | GRM4SCN10A | |
| SCHEMBL31316087 | 0.69 | HTR1A (0.52) | GRM4PDE10AHTR2AHTR2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023217230-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |