Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26200345 | 0.80 | AGTR1 (0.33) | AGTR1ALDH1A1SMN1; SMN2HTR2A | |
| SCHEMBL5671922 | 0.78 | MEN1 (0.37) | ALDH1A1SMN1; SMN2HTR2A | |
| SCHEMBL23536695 | 0.75 | IDO1 (0.33) | ALDH1A1 | |
| SCHEMBL286513 | 0.75 | CYP4F2 (0.33) | HTR2A | |
| SCHEMBL30681397 | 0.73 | PKM (0.35) | ALDH1A1HTR2A | |
| SCHEMBL2235036 | 0.73 | PKM (0.39) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL485713 | 0.73 | PKM (0.35) | ALDH1A1HTR2A | |
| SCHEMBL30681287 | 0.73 | PKM (0.39) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8357239 | 0.72 | AGTR1 (0.36) | AGTR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL23064180 | 0.70 | KDM1A (0.35) | IMPDH2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4358963-A1 | SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022271679-A1 | SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |
| EP-4076418-A1 | SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |
| WO-2021127429-A1 | SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2021-06-24 | — | — | WO | disclosed |