Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BMP1 | P13497 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3258334 | 0.84 | CA2 (0.50) | LMNAALDH1A1SMN1; SMN2CA1CA2 | |
| SCHEMBL2075495 | 0.79 | ALDH1A1 (0.45) | LMNAALDH1A1CA1CA2TSHR | |
| SCHEMBL13527822 | 0.77 | CA2 (0.50) | LMNAALDH1A1SMN1; SMN2HTTCA1 | |
| SCHEMBL17891745 | 0.77 | CA2 (0.44) | LMNAALDH1A1SMN1; SMN2CA1CA2 | |
| SCHEMBL6991225 | 0.77 | CA1 (0.48) | LMNAALDH1A1CA1CA2TSHR | |
| SCHEMBL8337020 | 0.77 | CA2 (0.60) | LMNAALDH1A1SMN1; SMN2HTTCA2 | |
| SCHEMBL5326194 | 0.77 | CA2 (0.42) | LMNAALDH1A1SMN1; SMN2CA1CA2 | |
| SCHEMBL5326198 | 0.75 | CA2 (0.44) | LMNAALDH1A1SMN1; SMN2HTTCA1 | |
| SCHEMBL1284072 | 0.75 | CA1 (0.43) | LMNAALDH1A1CA1CA2TSHR | |
| SCHEMBL5647044 | 0.75 | ALDH1A1 (0.50) | LMNAALDH1A1SMN1; SMN2HTTCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127333-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |