Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.42 |
| ▸ | HTR1D | P28221 | 2/20 | 0.41 |
| ▸ | HTR1B | P28222 | 2/20 | 0.41 |
| ▸ | HTR1F | P30939 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2346187 | 0.83 | HTR2C (0.58) | HTR1DHTR1BHTR1FHTR1ACCR2 | |
| SCHEMBL23536547 | 0.82 | PDE10A (0.37) | PDE10AHTR1DHTR1BHTR1FHTR1A | |
| SCHEMBL3227421 | 0.81 | PDE10A (0.42) | PDE10AHTR1DHTR1BHTR1FHTR1A | |
| SCHEMBL23536621 | 0.80 | PDE10A (0.38) | PDE10AHTR1DHTR1BHTR1FHTR1A | |
| SCHEMBL3257683 | 0.79 | HTR1F (0.65) | HTR1DHTR1BHTR1FHTR1A | |
| SCHEMBL30909178 | 0.79 | HTR1F (0.65) | HTR1DHTR1BHTR1FHTR1A | |
| SCHEMBL31295113 | 0.78 | HTR2C (0.48) | HTR1DHTR1BHTR1FHTR1ACCR2 | |
| SCHEMBL3215983 | 0.77 | HTR1A (0.50) | HTR1DHTR1BHTR1FHTR1ACCR2 | |
| SCHEMBL3217354 | 0.77 | HTR1A (0.50) | HTR1DHTR1BHTR1FHTR1ACCR2 | |
| SCHEMBL2433686 | 0.76 | IRAK4 (0.39) | PDE10AHTR1DHTR1BHTR1FHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127333-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |