Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23536622 | 0.77 | IDO1 (0.33) | — | |
| SCHEMBL25923518 | 0.71 | GLA (0.39) | GLAPOLBGAATSHR | |
| SCHEMBL16727137 | 0.71 | RPS6KB1 (0.31) | — | |
| SCHEMBL27318016 | 0.69 | GLA (0.35) | GLAPOLBGAATSHRALDH1A1 | |
| SCHEMBL31477237 | 0.69 | PTP4A3 (0.39) | GAATSHR | |
| SCHEMBL16454234 | 0.69 | KDM4E (0.36) | GLATSHRALDH1A1 | |
| SCHEMBL21598907 | 0.67 | NPSR1 (0.32) | GLAALDH1A1 | |
| SCHEMBL17808200 | 0.66 | HPGD (0.33) | GLAGAAALDH1A1 | |
| SCHEMBL31089280 | 0.66 | MAPT (0.40) | POLBGAAMAPT | |
| SCHEMBL24885610 | 0.65 | GLA (0.41) | GLAPOLBGAATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076418-A1 | SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |
| WO-2021127429-A1 | SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2021-06-24 | — | — | WO | disclosed |