Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13436405 | 0.79 | TSHR (0.38) | GLAPOLBGAATSHRKIF11 | |
| SCHEMBL26842934 | 0.75 | ALDH1A1 (0.31) | — | |
| SCHEMBL30950877 | 0.74 | GAA (0.55) | GLAPOLBGAATSHRKIF11 | |
| SCHEMBL2790893 | 0.74 | GAA (0.55) | GLAPOLBGAATSHRKIF11 | |
| SCHEMBL25711059 | 0.73 | GLA (0.36) | GLAPOLBGAATSHRKIF11 | |
| SCHEMBL24118125 | 0.73 | TSHR (0.46) | GLAPOLBGAATSHRKIF11 | |
| SCHEMBL26053513 | 0.72 | GLA (0.35) | GLAPOLBGAATSHRKIF11 | |
| SCHEMBL23536726 | 0.71 | GLA (0.32) | GLAPOLBGAATSHR | |
| SCHEMBL24885610 | 0.71 | GLA (0.41) | GLAPOLBGAATSHRKIF11 | |
| SCHEMBL31423301 | 0.71 | KIF11 (0.39) | GLAPOLBGAATSHRKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |