SCHEMBL23536751

SCHEMBL23536751

Cc1c(S(N)(=O)=O)ccc(S(=O)(=O)n2cc(C3CCC4(CC3)COCCO4)c3ncccc32)c1C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.33
FTO Q9C0B1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23536759 0.81 HTR6 (0.33) HTR6
SCHEMBL23536573 0.81 HTR6 (0.33) HTR6
SCHEMBL23536836 0.69 HTR6 (0.35) HTR6
SCHEMBL23536621 0.65 PDE10A (0.38)
SCHEMBL23536763 0.65 HTR6 (0.40) HTR6
SCHEMBL23570339 0.63 GPR119 (0.37) HTR6
SCHEMBL23570338 0.63 GPR119 (0.37) HTR6
SCHEMBL3225017 0.63 HTR6 (0.33) HTR6
SCHEMBL23536640 0.63 HTR6 (0.35) HTR6
SCHEMBL7946592 0.63 HTR6 (0.45) HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021127333-A1 TRPML MODULATORS CASMA THERAPEUTICS, INC. (US) 2021-06-24 WO disclosed