Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25839679 | 0.70 | CASP3 (0.37) | — | |
| SCHEMBL24252421 | 0.68 | — | — | |
| SCHEMBL30451438 | 0.68 | — | — | |
| SCHEMBL23526206 | 0.68 | KDM1A (0.31) | KDM1AKDM1B | |
| SCHEMBL23526022 | 0.68 | KDM1A (0.31) | KDM1AKDM1B | |
| SCHEMBL30014064 | 0.68 | KDM1A (0.31) | KDM1AKDM1B | |
| SCHEMBL31678471 | 0.67 | ALDH1A1 (0.57) | FLT1EGFR | |
| SCHEMBL26776186 | 0.66 | NQO2 (0.33) | — | |
| SCHEMBL8404450 | 0.66 | CYP1A2 (0.42) | — | |
| SCHEMBL10078329 | 0.66 | CYP1A2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4076418-A1 | SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2022-10-26 | — | — | EP | disclosed |
| WO-2021127429-A1 | SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2021-06-24 | — | — | WO | disclosed |