Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11377331 | 0.84 | MAPK1 (0.59) | MAPTL3MBTL1ATMALDH1A1POLB | |
| SCHEMBL18714222 | 0.83 | POLB (0.51) | PKMMAPTPOLBMAPK1KDM4E | |
| SCHEMBL29060088 | 0.83 | MAPT (0.42) | SMN1; SMN2MAPTL3MBTL1ALDH1A1POLB | |
| SCHEMBL11720643 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2PKMGPR35MAPTNPC1 | |
| SCHEMBL11377339 | 0.81 | MAPT (0.50) | SMN1; SMN2MAPTL3MBTL1ALDH1A1POLB | |
| SCHEMBL29028919 | 0.79 | MAPK1 (0.51) | SMN1; SMN2MAPTL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL31347580 | 0.78 | ATM (0.50) | SMN1; SMN2MAPTL3MBTL1ATMALDH1A1 | |
| SCHEMBL8272321 | 0.78 | ATM (0.50) | SMN1; SMN2MAPTL3MBTL1ATMALDH1A1 | |
| SCHEMBL18371184 | 0.77 | MAPT (0.47) | PKMMAPTL3MBTL1ATMPOLB | |
| SCHEMBL31306918 | 0.76 | ATM (0.53) | SMN1; SMN2L3MBTL1ATMALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127397-A1 | NITROGEN HETEROCYCLIC COMPOUNDS AND METHODS OF USE | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |