Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19172618 | 0.83 | POLB (0.44) | SMN1; SMN2POLBPKMALDH1A1MAPT | |
| SCHEMBL23537652 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2GPR35KDM4EPOLBPKM | |
| SCHEMBL24993698 | 0.76 | NOS3 (0.41) | SMN1; SMN2KDM4EPOLBALDH1A1MAPT | |
| SCHEMBL25336188 | 0.75 | ALDH1A1 (0.44) | SMN1; SMN2GPR35KDM4EALDH1A1GAA | |
| SCHEMBL27398497 | 0.73 | NPC1 (0.38) | SMN1; SMN2KDM4EALDH1A1GAANPC1 | |
| SCHEMBL2267794 | 0.73 | POLB (0.51) | SMN1; SMN2GPR35KDM4EPOLBPKM | |
| SCHEMBL1231901 | 0.73 | ALDH1A1 (0.51) | SMN1; SMN2SLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL131620 | 0.73 | GPR35 (0.57) | SMN1; SMN2GPR35KDM4EPOLBPKM | |
| SCHEMBL31215172 | 0.73 | GPR35 (0.57) | SMN1; SMN2GPR35KDM4EPOLBPKM | |
| SCHEMBL761929 | 0.72 | SMN1; SMN2 (0.57) | SMN1; SMN2GPR35KDM4EPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053608-A | 3-NITROPYRIDINE CARBOXAMIDES, POULTRY FEED | SANKYO COMPANY LIMITED (JA) | 1977-10-11 | — | — | US | disclosed |